# | Name | Compound Key | Action Type | Relation | Activity Value | Units | Assay ID | Assay Description | Comment | Assay | Assay Organism | |
---|---|---|---|---|---|---|---|---|---|---|---|---|
1. | ALA4067927 | 11l | Ratio IC50 | > | 200 | ALA4029885 | ||||||
2. | ALA4067927 | 11l | Drug uptake | = | 2.63 | nM | ALA4029898 | nM | ||||
3. | ALA4067927 | 11l | Cp | = | 13.8 | uM | ALA4029897 | uM | ||||
4. | ALA4067927 | 11l | INH | 0 | ALA4029891 | Not Active | % | Homo sapiens | ||||
5. | ALA4067927 | 11l | INH | 0 | ALA4029890 | Not Active | % | Homo sapiens | ||||
6. | ALA4067927 | 11l | INH | 0 | ALA4029889 | Not Active | % | Homo sapiens | ||||
7. | ALA4067927 | 11l | INH | 0 | ALA4029888 | Not Active | % | Homo sapiens | ||||
8. | ALA4067927 | 11l | INH | 0 | ALA4029882 | Not Active | % | Homo sapiens | ||||
9. | ALA4067927 | 11l | INH | = | 26 | % | ALA4029893 | % | Cavia porcellus | |||
10. | ALA4067927 | 11l | INH | = | 17 | % | ALA4029887 | % | Homo sapiens | |||
11. | ALA4067927 | 11l | t1/2 | = | 6.77 | hr | ALA4029878 | hr | Rattus norvegicus | |||
12. | ALA4067927 | 11l | F | = | 85 | % | ALA4029877 | % | Rattus norvegicus | |||
13. | ALA4067927 | 11l | Tmax | = | 4 | hr | ALA4029876 | hr | Rattus norvegicus | |||
14. | ALA4067927 | 11l | AUC | = | 12380 | ng.hr/ml | ALA4029875 | ng.hr.mL-1 | Rattus norvegicus | |||
15. | ALA4067927 | 11l | Cmax | = | 1176 | ng/ml | ALA4029874 | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | nM | Rattus norvegicus | ||
16. | ALA4067927 | 11l | IC50 | = | 36.28 | nM | ALA4029858 | 7.44 | nM | Homo sapiens | ||
17. | ALA4067927 | 11l | IC50 | = | 838.7 | nM | ALA4029859 | 6.08 | nM | Homo sapiens | ||
18. | ALA4067927 | 11l | IC50 | = | 0.06 | uM | ALA4029860 | 7.22 | nM | Homo sapiens | ||
19. | ALA4067927 | 11l | IC50 | = | 9.88 | uM | ALA4029861 | 5.00 | nM | Homo sapiens | ||
20. | ALA4067927 | 11l | Stability | = | 76 | % | ALA4029862 | % | Homo sapiens |