# | Name | Compound Key | Action Type | Relation | Activity Value | Units | Assay ID | Assay Description | Comment | Assay | Assay Organism | |
---|---|---|---|---|---|---|---|---|---|---|---|---|
1. | ALA4068397 | BDBM254203 | ED50 | = | 0.9 | mg kg-1 | ALA4054739 | mg.kg-1 | Rattus norvegicus | |||
2. | ALA4068397 | BDBM254203 | Occ | 0 | ALA4054739 | Dose-dependent effect | Rattus norvegicus | |||||
3. | ALA4068397 | BDBM254203 | pKi | = | 8.66 | ALA4054758 | 8.66 | nM | Rattus norvegicus | |||
4. | ALA4068397 | BDBM254203 | pKi | = | 7.89 | ALA4054759 | 7.89 | nM | Homo sapiens | |||
5. | ALA4068397 | BDBM254203 | Activity | 0 | ALA4054709 | Toxic | Rattus norvegicus | |||||
6. | ALA4068397 | BDBM254203 | Activity | 0 | ALA4054710 | Toxic | Rattus norvegicus | |||||
7. | ALA4068397 | BDBM254203 | Activity | 0 | ALA4054711 | Toxic | Rattus norvegicus | |||||
8. | ALA4068397 | BDBM254203 | Activity | 0 | ALA4054713 | Toxic | Rattus norvegicus | |||||
9. | ALA4068397 | BDBM254203 | Cp | = | 175 | uM | ALA4054712 | uM | Rattus norvegicus | |||
10. | ALA4068397 | BDBM254203 | Activity | 0 | ALA4054714 | Toxic | Rattus norvegicus | |||||
11. | ALA4068397 | BDBM254203 | Drug metabolism | 0 | ALA4054715 | Metabolite_Detected | Homo sapiens | |||||
12. | ALA4068397 | BDBM254203 | Drug metabolism | 0 | ALA4054716 | Metabolite_Detected | Homo sapiens | |||||
13. | ALA4068397 | BDBM254203 | Drug metabolism | 0 | ALA4054718 | Metabolite_Detected | Rattus norvegicus | |||||
14. | ALA4068397 | BDBM254203 | Drugexcretion | = | 0.4 | % | ALA4054719 | % | Rattus norvegicus | |||
15. | ALA4068397 | BDBM254203 | F | = | 5 | % | ALA4054721 | % | Macaca fascicularis | |||
16. | ALA4068397 | BDBM254203 | F | = | 61 | % | ALA4054720 | % | Mus musculus | |||
17. | ALA4068397 | BDBM254203 | F | = | 70 | % | ALA4054722 | % | Canis lupus familiaris | |||
18. | ALA4068397 | BDBM254203 | t1/2 | = | 0.8 | hr | ALA4054724 | hr | Macaca fascicularis | |||
19. | ALA4068397 | BDBM254203 | t1/2 | = | 0.4 | hr | ALA4054723 | hr | Mus musculus | |||
20. | ALA4068397 | BDBM254203 | t1/2 | = | 11 | hr | ALA4054725 | hr | Canis lupus familiaris |