# | Name | Compound Key | Action Type | Relation | Activity Value | Units | Assay ID | Assay Description | Comment | Assay | Assay Organism | |
---|---|---|---|---|---|---|---|---|---|---|---|---|
1. | ALA4068937 | 13 | Activity | 0 | ALA4021717 | Dose-dependent effect | Mus musculus | |||||
2. | ALA4068937 | 13 | Ratio | = | 50 | ALA4021716 | ||||||
3. | ALA4068937 | 13 | IC50 | = | 30 | nM | ALA4021715 | 7.52 | nM | Mus musculus | ||
4. | ALA4068937 | 13 | fIC50 | = | 1.5 | uM | ALA4021714 | uM | Mus musculus | |||
5. | ALA4068937 | 13 | Fu | = | 0.065 | ALA4021713 | Mus musculus | |||||
6. | ALA4068937 | 13 | IC50 | = | 23 | uM | ALA4021712 | 4.64 | nM | Mus musculus | ||
7. | ALA4068937 | 13 | IC50 | = | 29 | nM | ALA4021711 | 7.54 | nM | Homo sapiens | ||
8. | ALA4068937 | 13 | Activity | 0 | ALA4021710 | Not Active | ||||||
9. | ALA4068937 | 13 | IC50 | = | 21 | nM | ALA4021709 | 7.68 | nM | Homo sapiens | ||
10. | ALA4068937 | 13 | Activity | 0 | ALA4021707 | Active | Mus musculus | |||||
11. | ALA4068937 | 13 | Papp | < | 2 | 10'-6 cm/s | ALA4021706 | 10'-6 cm/s | ||||
12. | ALA4068937 | 13 | F | = | 2 | % | ALA4021705 | % | Rattus norvegicus | |||
13. | ALA4068937 | 13 | t1/2 | = | 0.8 | hr | ALA4021704 | hr | Rattus norvegicus | |||
14. | ALA4068937 | 13 | Fu | = | 0.133 | ALA4021703 | Rattus norvegicus | |||||
15. | ALA4068937 | 13 | CL free | = | 360 | ml/min.kg | ALA4021702 | mL.min-1.kg-1 | Rattus norvegicus | |||
16. | ALA4068937 | 13 | Ratio | = | 0 | % | ALA4021701 | % | ||||
17. | ALA4068937 | 13 | BPR | = | 1 | % | ALA4021691 | % | ||||
18. | ALA4068937 | 13 | Activity | 0 | ALA4021692 | Not Active | Homo sapiens | |||||
19. | ALA4068937 | 13 | Activity | 0 | ALA4021700 | Not Active | Homo sapiens | |||||
20. | ALA4068937 | 13 | Activity | 0 | ALA4021699 | Not Active | Homo sapiens |