# | Name | Compound Key | Action Type | Relation | Activity Value | Units | Assay ID | Assay Description | Comment | Assay | Assay Organism | |
---|---|---|---|---|---|---|---|---|---|---|---|---|
1. | ALA4070442 | 12 | INH | 0 | ALA4019549 | Dose-dependent effect | % | Rattus norvegicus | ||||
2. | ALA4070442 | 12 | INH | 0 | ALA4019548 | Dose-dependent effect | % | Rattus norvegicus | ||||
3. | ALA4070442 | 12 | pED50 | = | 1.2 | ALA4019549 | Rattus norvegicus | |||||
4. | ALA4070442 | 12 | pED50 | = | 1.48 | ALA4019548 | Rattus norvegicus | |||||
5. | ALA4070442 | 12 | pIC50 | = | 6.41 | ALA4019558 | 6.41 | nM | Homo sapiens | |||
6. | ALA4070442 | 12 | pIC50 | = | 6.5 | ALA4019530 | 6.50 | nM | Homo sapiens | |||
7. | ALA4070442 | 12 | pIC50 | = | 6.3 | ALA4019533 | 6.30 | nM | Rattus norvegicus | |||
8. | ALA4070442 | 12 | CLH(app) | < | 8 | microL/min/mg | ALA4019559 | mL.min-1.g-1 | Rattus norvegicus | |||
9. | ALA4070442 | 12 | IC50 | = | 0.39 | uM | ALA4019558 | 6.41 | nM | Homo sapiens | ||
10. | ALA4070442 | 12 | IC50 | = | 0.45 | uM | ALA4019530 | 6.35 | nM | Homo sapiens | ||
11. | ALA4070442 | 12 | INH | 0 | ALA4019557 | Not Active | % | Homo sapiens | ||||
12. | ALA4070442 | 12 | INH | 0 | ALA4019556 | Not Active | % | Homo sapiens | ||||
13. | ALA4070442 | 12 | INH | 0 | ALA4019555 | Not Active | % | Homo sapiens | ||||
14. | ALA4070442 | 12 | INH | 0 | ALA4019554 | Not Active | % | Homo sapiens | ||||
15. | ALA4070442 | 12 | IC50 | = | 0.34 | uM | ALA4019533 | 6.47 | nM | Rattus norvegicus | ||
16. | ALA4070442 | 12 | CLH(app) | < | 8 | microL/min/mg | ALA4019534 | mL.min-1.g-1 | Homo sapiens | |||
17. | ALA4070442 | 12 | logD | = | 2.2 | ALA4019535 | ||||||
18. | ALA4070442 | 12 | Papp | = | 3.5 | 10'-6 cm/s | ALA4019536 | 10'-6 cm/s | Canis lupus familiaris | |||
19. | ALA4070442 | 12 | Therm_solubility | = | 503 | uM | ALA4019537 | nM | ||||
20. | ALA4070442 | 12 | Fu | = | 0.13 | ALA4019538 | Homo sapiens |