Activities

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Activities

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#	Name	Compound Key	Action Type	Relation	Activity Value	Units	Assay ID	Assay Description	Comment	Assay	Assay Organism
1.	tirabrutinib	TIRABRUTINIB	Ratio IC50	=	0.5		ALA5251931
2.	tirabrutinib	TIRABRUTINIB	Ratio IC50	>	345		ALA5251930
3.	tirabrutinib	TIRABRUTINIB	IC50	=	14.3	nM	ALA5251929	7.84		nM	Homo sapiens
4.	tirabrutinib	TIRABRUTINIB	IC50	>	10000	nM	ALA5251928			nM	Homo sapiens
5.	tirabrutinib	TIRABRUTINIB	IC50	=	29	nM	ALA5251905	7.54		nM	Homo sapiens
6.	tirabrutinib	TIRABRUTINIB	IC50	>	1000	nM	ALA5127263			nM	Homo sapiens
7.	tirabrutinib	TIRABRUTINIB	IC50	=	1133	nM	ALA5127262	5.95		nM	Homo sapiens
8.	tirabrutinib	TIRABRUTINIB	IC50	=	991	nM	ALA5127261	6.00		nM	Homo sapiens
9.	tirabrutinib	TIRABRUTINIB	IC50	>	1000	nM	ALA5127260			nM	Homo sapiens
10.	tirabrutinib	TIRABRUTINIB	IC50	>	1000	nM	ALA5127259			nM	Homo sapiens
11.	tirabrutinib	TIRABRUTINIB	IC50	=	4.3	nM	ALA5127258	8.37		nM	Homo sapiens
12.	tirabrutinib	TIRABRUTINIB	IC50	=	116	nM	ALA5127257	6.94		nM	Homo sapiens
13.	tirabrutinib	TIRABRUTINIB	IC50	>	1000	nM	ALA5127256			nM	Homo sapiens
14.	tirabrutinib	TIRABRUTINIB	IC50	=	77	nM	ALA5127255	7.11		nM	Homo sapiens
15.	tirabrutinib	TIRABRUTINIB	IC50	=	5.6	nM	ALA5127254	8.25		nM	Homo sapiens
16.	tirabrutinib	TIRABRUTINIB	IC50	=	363	nM	ALA4358574	6.44		nM	Homo sapiens
17.	tirabrutinib	TIRABRUTINIB	Activity		0		ALA4358573		Active		Homo sapiens
18.	tirabrutinib	TIRABRUTINIB	Selectivity ratio	>	714		ALA4358528
19.	tirabrutinib	TIRABRUTINIB	Selectivity ratio	>	714		ALA4358527
20.	tirabrutinib	TIRABRUTINIB	Selectivity ratio	=	44		ALA4358526