Activities

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Activities

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#	Name	Compound Key	Action Type	Relation	Activity Value	Units	Assay ID	Assay Description	Assay	Assay Organism
1.	ALA4073137	19a	EC50	=	20	nM	ALA4004022	7.70	nM	Homo sapiens
2.	ALA4073137	19a	Emax	=	87	%	ALA4004023		%	Homo sapiens
3.	ALA4073137	19a	IC50	>	20000	nM	ALA4004024		nM	Homo sapiens
4.	ALA4073137	19a	IC50	>	20000	nM	ALA4004025		nM	Homo sapiens
5.	ALA4073137	19a	IC50	>	60000	nM	ALA4004026		nM	Homo sapiens
6.	ALA4073137	19a	IC50	>	30000	nM	ALA4004027		nM	Homo sapiens
7.	ALA4073137	19a	IC50	>	10000	nM	ALA4004028		nM	Homo sapiens
8.	ALA4073137	19a	A50	=	54	uM	ALA4004029		uM	Homo sapiens
9.	ALA4073137	19a	EC50	=	339	nM	ALA4004030	6.47	nM	Homo sapiens
10.	ALA4073137	19a	CL	=	71	ml/min.kg	ALA4004032		mL.min-1.kg-1	Rattus norvegicus
11.	ALA4073137	19a	CL free	=	148	ml/min.kg	ALA4004034		mL.min-1.kg-1	Rattus norvegicus
12.	ALA4073137	19a	Vd	=	19	L/Kg	ALA4004031		L.kg-1	Rattus norvegicus
13.	ALA4073137	19a	t1/2	=	2.6	hr	ALA4004036		hr	Rattus norvegicus
14.	ALA4073137	19a	AUC/dose	=	0.35	microM.hr/mg/kg	ALA4004038		microM.hr/mg/kg	Rattus norvegicus
15.	ALA4073137	19a	fAUC/dose	=	0.17	microM.hr/mg/kg	ALA4004039		microM.hr/mg/kg	Rattus norvegicus
16.	ALA4073137	19a	F	=	71	%	ALA4004040		%	Rattus norvegicus
17.	ALA4073137	19a	Fu	=	48	%	ALA4004041			Rattus norvegicus
18.	ALA4073137	19a	CL	=	7.9	ml/min.kg	ALA4004042		mL.min-1.kg-1	Canis lupus familiaris
19.	ALA4073137	19a	Fu	=	42	%	ALA4004057			Macaca mulatta
20.	ALA4073137	19a	Fu	=	48	%	ALA4004056			Canis lupus familiaris