Activities

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Activities

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#	Name	Compound Key	Action Type	Relation	Activity Value	Units	Assay ID	Assay Description	Comment	Assay	Assay Organism
1.	ALA4074304	BDBM254189	ED50	=	0.3	mg kg-1	ALA4054742			mg.kg-1	Rattus norvegicus
2.	ALA4074304	BDBM254189	IC50	=	2.3	uM	ALA4054732	5.64		nM	Homo sapiens
3.	ALA4074304	BDBM254189	pIC50	=	8.46		ALA4054759	8.46		nM	Homo sapiens
4.	ALA4074304	BDBM254189	pIC50	=	8.04		ALA4054758	8.04		nM	Rattus norvegicus
5.	ALA4074304	BDBM254189	IC50	>	10	uM	ALA4054757			nM	Homo sapiens
6.	ALA4074304	BDBM254189	PPB	=	93.7	%	ALA4054756			%	Rattus norvegicus
7.	ALA4074304	BDBM254189	IC50	>	10	uM	ALA4054733			nM	Homo sapiens
8.	ALA4074304	BDBM254189	IC50	>	10	uM	ALA4054734			nM	Homo sapiens
9.	ALA4074304	BDBM254189	IC50	>	10	uM	ALA4054736			nM	Homo sapiens
10.	ALA4074304	BDBM254189	IC50	=	4.3	uM	ALA4054735	5.37		nM	Homo sapiens
11.	ALA4074304	BDBM254189	IC50	>	10	uM	ALA4054737			nM	Homo sapiens
12.	ALA4074304	BDBM254189	INH		0		ALA4054741		Dose-dependent effect	%	Rattus norvegicus
13.	ALA4074304	BDBM254189	Occ		0		ALA4054742		Dose-dependent effect		Rattus norvegicus
14.	ALA4074304	BDBM254189	F	=	65	%	ALA4054744			%	Canis lupus familiaris
15.	ALA4074304	BDBM254189	F	=	77	%	ALA4054743			%	Rattus norvegicus
16.	ALA4074304	BDBM254189	t1/2	=	2.4	hr	ALA4054745			hr	Canis lupus familiaris
17.	ALA4074304	BDBM254189	t1/2	=	1.5	hr	ALA4054747			hr	Rattus norvegicus
18.	ALA4074304	BDBM254189	Vdss	=	3.3	L/Kg	ALA4054746			L.kg-1	Canis lupus familiaris
19.	ALA4074304	BDBM254189	Vdss	=	3	L/Kg	ALA4054748			L.kg-1	Rattus norvegicus
20.	ALA4074304	BDBM254189	CL	=	33	ml/min.kg	ALA4054749			mL.min-1.kg-1	Canis lupus familiaris