| # | Name | Compound Key | Action Type | Relation | Activity Value | Units | Assay ID | Assay Description | Comment | Assay | Assay Organism | |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1. |  ALA4074744 | 27 | INH | 0 | ALA4008529 | Dose-dependent effect | % | Rattus norvegicus | ||||
| 2. | ALA4074744 | 27 | Activity | 0 | ALA4008546 | Non-Toxic | Rattus norvegicus | |||||
| 3. | ALA4074744 | 27 | Activity | 0 | ALA4008545 | Non-Toxic | Rattus norvegicus | |||||
| 4. | ALA4074744 | 27 | Activity | 0 | ALA4008544 | Not Active | Rattus norvegicus | |||||
| 5. | ALA4074744 | 27 | Activity | 0 | ALA4008543 | Active | Rattus norvegicus | |||||
| 6. | ALA4074744 | 27 | Fu | = | 4 | % | ALA4008542 | Rattus norvegicus | ||||
| 7. | ALA4074744 | 27 | Fu | = | 8 | % | ALA4008541 | Rattus norvegicus | ||||
| 8. | ALA4074744 | 27 | Cp | = | 450 | nM | ALA4008540 | nM | Rattus norvegicus | |||
| 9. | ALA4074744 | 27 | Drug uptake | = | 15 | nM | ALA4008539 | nM | Rattus norvegicus | |||
| 10. | ALA4074744 | 27 | Drug uptake | = | 66 | nM | ALA4008538 | nM | Rattus norvegicus | |||
| 11. | ALA4074744 | 27 | AUC | = | 442 | ng.hr/ml | ALA4008537 | ng.hr.mL-1 | Rattus norvegicus | |||
| 12. | ALA4074744 | 27 | Cmax | = | 201 | ng/ml | ALA4008536 | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | nM | Rattus norvegicus | ||
| 13. | ALA4074744 | 27 | Tmax | = | 0.67 | hr | ALA4008535 | hr | Rattus norvegicus | |||
| 14. | ALA4074744 | 27 | F | = | 87 | % | ALA4008528 | % | Rattus norvegicus | |||
| 15. | ALA4074744 | 27 | CL | = | 50 | % | ALA4008534 | % | Rattus norvegicus | |||
| 16. | ALA4074744 | 27 | CL | = | 32.8 | ml/min.kg | ALA4008533 | mL.min-1.kg-1 | Rattus norvegicus | |||
| 17. | ALA4074744 | 27 | Vdss | = | 0.98 | L/Kg | ALA4008532 | L.kg-1 | Rattus norvegicus | |||
| 18. | ALA4074744 | 27 | beta t1/2 | = | 1.01 | hr | ALA4008531 | hr | Rattus norvegicus | |||
| 19. | ALA4074744 | 27 | AUC | = | 508 | ng.hr/ml | ALA4008530 | ng.hr.mL-1 | Rattus norvegicus | |||
| 20. | ALA4074744 | 27 | EC50 | = | 0.67 | uM | ALA4008529 | 6.17 | nM | Rattus norvegicus |
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