| # | Name | Compound Key | Action Type | Relation | Activity Value | Units | Assay ID | Assay Description | Comment | Assay | Assay Organism | |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1. |  ALA4074883 | 72 | Drug uptake | = | 18 | % | ALA4038086 | % | Rattus norvegicus | |||
| 2. | ALA4074883 | 72 | Drug uptake | = | 20 | % | ALA4038085 | % | Rattus norvegicus | |||
| 3. | ALA4074883 | 72 | Drug uptake | = | 36 | % | ALA4038084 | % | Rattus norvegicus | |||
| 4. | ALA4074883 | 72 | Activity | 0 | ALA4038080 | Dose-dependent effect | Mustela putorius furo | |||||
| 5. | ALA4074883 | 72 | Activity | 0 | ALA4038079 | Non-Toxic | Mustela putorius furo | |||||
| 6. | ALA4074883 | 72 | FC | = | 1.3 | ALA4038078 | Rattus norvegicus | |||||
| 7. | ALA4074883 | 72 | FC | = | 0.7 | ALA4038077 | Rattus norvegicus | |||||
| 8. | ALA4074883 | 72 | Imax | = | 35 | % | ALA4038076 | % | Rattus norvegicus | |||
| 9. | ALA4074883 | 72 | INH | = | 58 | % | ALA4038075 | % | Rattus norvegicus | |||
| 10. | ALA4074883 | 72 | Cp | < | 5 | ng/ml | ALA4038074 | ng/ml | Rattus norvegicus | |||
| 11. | ALA4074883 | 72 | Drug uptake | = | 15 | % | ALA4038073 | % | Rattus norvegicus | |||
| 12. | ALA4074883 | 72 | Vdss | = | 3.9 | L/Kg | ALA4038070 | L.kg-1 | Rattus norvegicus | |||
| 13. | ALA4074883 | 72 | Therm_solubility | = | 4 | ug ml-1 | ALA4038066 | ug.mL-1 | ||||
| 14. | ALA4074883 | 72 | Papp | = | 0.15 | 10'-6 cm/s | ALA4038065 | 10'-6 cm/s | ||||
| 15. | ALA4074883 | 72 | IC50 | = | 0.12 | nM | ALA4038063 | 9.92 | nM | |||
| 16. | ALA4074883 | 72 | IC50 | = | 0.17 | nM | ALA4038064 | 9.77 | nM | Homo sapiens | ||
| 17. | ALA4074883 | 72 | t1/2 | = | 0.9 | hr | ALA4038071 | hr | Rattus norvegicus | |||
| 18. | ALA4074883 | 72 | CL | = | 78 | ml/min.kg | ALA4038072 | mL.min-1.kg-1 | Rattus norvegicus | |||
| 19. | ALA4074883 | 72 | AUC | = | 108 | ng.hr/ml | ALA4038069 | ng.hr.mL-1 | Rattus norvegicus | |||
| 20. | ALA4074883 | 72 | Cmax | = | 118 | ng/ml | ALA4038068 | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | nM | Rattus norvegicus |
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