# | Name | Compound Key | Action Type | Relation | Activity Value | Units | Assay ID | Assay Description | Comment | Assay | Assay Organism | |
---|---|---|---|---|---|---|---|---|---|---|---|---|
1. | ALA4075121 | 69 | MIC | = | 16 | ug ml-1 | ALA4019723 | ug.mL-1 | Trichophyton mentagrophytes | |||
2. | ALA4075121 | 69 | MIC | = | 16 | ug ml-1 | ALA4019722 | ug.mL-1 | Trichophyton verrucosum | |||
3. | ALA4075121 | 69 | INH | 0 | ALA4019721 | Active | % | Staphylococcus aureus (strain Newman) | ||||
4. | ALA4075121 | 69 | Survival | = | 0.2 | % | ALA4019720 | % | ||||
5. | ALA4075121 | 69 | Survival | = | 0.12 | % | ALA4019719 | % | ||||
6. | ALA4075121 | 69 | Survival | = | 0.46 | % | ALA4019718 | % | Staphylococcus aureus (strain Mu50 / ATCC 700699) | |||
7. | ALA4075121 | 69 | Survival | = | 0.28 | % | ALA4019672 | % | Staphylococcus aureus (strain Newman) | |||
8. | ALA4075121 | 69 | Survival | = | 2.6 | % | ALA4019670 | % | Staphylococcus aureus | |||
9. | ALA4075121 | 69 | MIC | = | 16 | ug ml-1 | ALA4019715 | ug.mL-1 | Nannizzia gypsea | |||
10. | ALA4075121 | 69 | MIC | = | 16 | ug ml-1 | ALA4019714 | ug.mL-1 | Trichophyton rubrum | |||
11. | ALA4075121 | 69 | F | = | 6.5 | % | ALA4019713 | % | Rattus norvegicus | |||
12. | ALA4075121 | 69 | MRT | = | 3.28 | hr | ALA4019712 | hr | Rattus norvegicus | |||
13. | ALA4075121 | 69 | MRT | = | 1.13 | hr | ALA4019711 | hr | Rattus norvegicus | |||
14. | ALA4075121 | 69 | MRT(t) | = | 2.61 | hr | ALA4019710 | hr | Rattus norvegicus | |||
15. | ALA4075121 | 69 | MRT(t) | = | 0.9 | hr | ALA4019709 | hr | Rattus norvegicus | |||
16. | ALA4075121 | 69 | AUC | = | 177.02 | hr.ng/ml | ALA4019708 | ng.hr.mL-1 | Rattus norvegicus | |||
17. | ALA4075121 | 69 | AUC | = | 1362.33 | hr.ng/ml | ALA4019707 | ng.hr.mL-1 | Rattus norvegicus | |||
18. | ALA4075121 | 69 | AUCt | = | 156.46 | hr.ng/ml | ALA4019706 | ng.hr.mL-1 | Rattus norvegicus | |||
19. | ALA4075121 | 69 | AUCt | = | 1331.84 | hr.ng/ml | ALA4019705 | ng.hr.mL-1 | Rattus norvegicus | |||
20. | ALA4075121 | 69 | Cmax | = | 41.78 | ng/ml | ALA4019704 | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | nM | Rattus norvegicus |