# | Name | Compound Key | Action Type | Relation | Activity Value | Units | Assay ID | Assay Description | Comment | Assay | Assay Organism | |
---|---|---|---|---|---|---|---|---|---|---|---|---|
1. | ALA4075319 | 22 | IC50 | = | 0.017 | uM | ALA4030032 | 7.77 | nM | Homo sapiens | ||
2. | ALA4075319 | 22 | IC50 | = | 10.3 | uM | ALA4030033 | 4.99 | nM | Homo sapiens | ||
3. | ALA4075319 | 22 | Ratio IC50 | = | 606 | ALA4030034 | ||||||
4. | ALA4075319 | 22 | Activity | 0 | ALA4030064 | Active | Rattus norvegicus | |||||
5. | ALA4075319 | 22 | Ratio IC50 | = | 417 | ALA4030013 | ||||||
6. | ALA4075319 | 22 | Activity | 0 | ALA4030058 | Active | Rattus norvegicus | |||||
7. | ALA4075319 | 22 | Activity | 0 | ALA4030057 | Not Active | Rattus norvegicus | |||||
8. | ALA4075319 | 22 | F | = | 47 | % | ALA4030026 | % | Rattus norvegicus | |||
9. | ALA4075319 | 22 | t1/2 | = | 4.7 | hr | ALA4030025 | hr | Rattus norvegicus | |||
10. | ALA4075319 | 22 | AUC/dose | = | 1.8 | uM.hr.kg/mg | ALA4030024 | uM.hr.kg/mg | Rattus norvegicus | |||
11. | ALA4075319 | 22 | Vdss | = | 3 | L/Kg | ALA4030023 | L.kg-1 | Rattus norvegicus | |||
12. | ALA4075319 | 22 | CL | = | 9.6 | ml/min.kg | ALA4030022 | mL.min-1.kg-1 | Rattus norvegicus | |||
13. | ALA4075319 | 22 | Activity | = | -23 | mmHg | ALA4030020 | mmHg | Rattus norvegicus | |||
14. | ALA4075319 | 22 | IC50 | = | 9.6 | uM | ALA4030012 | 5.02 | nM | Homo sapiens | ||
15. | ALA4075319 | 22 | IC50 | = | 0.023 | uM | ALA4030011 | 7.64 | nM | Homo sapiens | ||
16. | ALA4075319 | 22 | CL | = | 24.4 | ml/min.kg | ALA4030059 | mL.min-1.kg-1 | Canis lupus familiaris | |||
17. | ALA4075319 | 22 | Vdss | = | 1.7 | L/Kg | ALA4030060 | L.kg-1 | Canis lupus familiaris | |||
18. | ALA4075319 | 22 | t1/2 | = | 1.3 | hr | ALA4030061 | hr | Canis lupus familiaris | |||
19. | ALA4075319 | 22 | Papp | = | 36 | 10^-6 cm/s | ALA5039910 | 10^-6 cm/s | ||||
20. | ALA4075319 | 22 | Ratio | = | 606 | ALA5039909 |