# | Name | Compound Key | Action Type | Relation | Activity Value | Units | Assay ID | Assay Description | Comment | Assay | Assay Organism | |
---|---|---|---|---|---|---|---|---|---|---|---|---|
1. | ALA4076428 | 51 | Ratio | = | 2.8 | ALA4037616 | ||||||
2. | ALA4076428 | 51 | K(p,uu,brain) | 0 | ALA4037534 | Not Determined | ||||||
3. | ALA4076428 | 51 | AUC/dose | = | 296 | ng.hr/g/mg/kg | ALA4037532 | ng.hr/g/mg/kg | Rattus norvegicus | |||
4. | ALA4076428 | 51 | Fu | = | 11.4 | % | ALA4037529 | Rattus norvegicus | ||||
5. | ALA4076428 | 51 | Fu | = | 0.65 | % | ALA4037530 | Rattus norvegicus | ||||
6. | ALA4076428 | 51 | pIC50 | = | 7 | ALA4037528 | 7.00 | nM | Homo sapiens | |||
7. | ALA4076428 | 51 | Kp | = | 0.03 | ALA4037533 | ||||||
8. | ALA4076428 | 51 | AUC/dose | = | 11721 | ng.hr/ml/mg/kg | ALA4037531 | ng.hr/ml/mg/kg | Rattus norvegicus | |||
9. | ALA4076428 | 51 | pIC50 | = | 9 | ALA4037524 | 9.00 | nM | Homo sapiens | |||
10. | ALA4076428 | 51 | solubility | = | 757.6 | ug ml-1 | ALA4037525 | ug.mL-1 | ||||
11. | ALA4076428 | 51 | permeability | = | 205 | nm/s | ALA4037527 | nm/s | Canis lupus familiaris |