# | Name | Compound Key | Action Type | Relation | Activity Value | Units | Assay ID | Assay Description | Comment | Assay | Assay Organism | |
---|---|---|---|---|---|---|---|---|---|---|---|---|
1. | ALA4076767 | 13 | logIC50 | = | 2.551 | ALA4050184 | Homo sapiens | |||||
2. | ALA4076767 | 13 | Activity | = | 26 | g | ALA4050222 | g | Mus musculus | |||
3. | ALA4076767 | 13 | Activity | = | 24 | g | ALA4050221 | g | Mus musculus | |||
4. | ALA4076767 | 13 | Activity | 0 | ALA4050220 | Active | Homo sapiens | |||||
5. | ALA4076767 | 13 | TGI | 0 | ALA4050219 | Active | Homo sapiens | |||||
6. | ALA4076767 | 13 | AUC | = | 8463 | hr.ng/ml | ALA4050218 | ng.hr.mL-1 | Mus musculus | |||
7. | ALA4076767 | 13 | beta t1/2 | = | 2.28 | hr | ALA4050217 | hr | Mus musculus | |||
8. | ALA4076767 | 13 | CL | = | 17.5 | L/hr/kg | ALA4050216 | mL.min-1.kg-1 | Mus musculus | |||
9. | ALA4076767 | 13 | solubility | = | 5 | mg/ml | ALA4050215 | ug.mL-1 | ||||
10. | ALA4076767 | 13 | solubility | = | 53.4 | mg/ml | ALA4050214 | ug.mL-1 | ||||
11. | ALA4076767 | 13 | INH | 0 | ALA4050208 | Active | % | Homo sapiens | ||||
12. | ALA4076767 | 13 | INH | 0 | ALA4050212 | Active | % | Homo sapiens | ||||
13. | ALA4076767 | 13 | INH | 0 | ALA4050210 | Active | % | Homo sapiens | ||||
14. | ALA4076767 | 13 | INH | 0 | ALA4050207 | Active | % | Homo sapiens | ||||
15. | ALA4076767 | 13 | Activity | = | 70 | % | ALA4050206 | % | Homo sapiens | |||
16. | ALA4076767 | 13 | INH | 0 | ALA4050205 | Dose-dependent effect | % | Homo sapiens | ||||
17. | ALA4076767 | 13 | INH | 0 | ALA4050204 | Dose-dependent effect | % | Homo sapiens | ||||
18. | ALA4076767 | 13 | IC50 | = | 4.06 | 10'-5M | ALA4050203 | 4.39 | nM | Homo sapiens | ||
19. | ALA4076767 | 13 | IC50 | = | 1.32 | 10'-4M | ALA4050199 | nM | Homo sapiens | |||
20. | ALA4076767 | 13 | IC50 | = | 1.53 | 10'-4M | ALA4050198 | nM | Homo sapiens |