# | Name | Compound Key | Action Type | Relation | Activity Value | Units | Assay ID | Assay Description | Comment | Assay | Assay Organism | |
---|---|---|---|---|---|---|---|---|---|---|---|---|
1. | ALA4077246 | 7f | MIC50 | = | 0.12 | ug ml-1 | ALA4056594 | ug.mL-1 | ||||
2. | ALA4077246 | 7f | MIC50 | = | 0.002 | ug ml-1 | ALA4056595 | ug.mL-1 | ||||
3. | ALA4077246 | 7f | MIC100 | = | 0.5 | ug ml-1 | ALA4056596 | ug ml-1 | Aspergillus | |||
4. | ALA4077246 | 7f | IC50 | > | 200 | uM | ALA4056597 | nM | Homo sapiens | |||
5. | ALA4077246 | 7f | IC50 | = | 138 | uM | ALA4056598 | nM | Homo sapiens | |||
6. | ALA4077246 | 7f | IC50 | > | 100 | uM | ALA4056599 | nM | Homo sapiens | |||
7. | ALA4077246 | 7f | IC50 | > | 100 | uM | ALA4056600 | nM | Homo sapiens | |||
8. | ALA4077246 | 7f | IC50 | = | 38 | uM | ALA4056601 | 4.42 | nM | Homo sapiens | ||
9. | ALA4077246 | 7f | IC50 | > | 100 | uM | ALA4056602 | nM | Homo sapiens | |||
10. | ALA4077246 | 7f | IC50 | > | 100 | uM | ALA4056603 | nM | Homo sapiens | |||
11. | ALA4077246 | 7f | Tmax | = | 4 | hr | ALA4056605 | hr | Mus musculus | |||
12. | ALA4077246 | 7f | Cmax | = | 2.5 | ug ml-1 | ALA4056606 | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | nM | Mus musculus | ||
13. | ALA4077246 | 7f | AUClast | = | 67 | microg.hr/mL | ALA4056607 | ng.hr.mL-1 | Mus musculus | |||
14. | ALA4077246 | 7f | t1/2 | = | 24 | hr | ALA4056608 | hr | Mus musculus | |||
15. | ALA4077246 | 7f | MIC50 | = | 0.25 | ug ml-1 | ALA4056590 | ug.mL-1 | Trichophyton rubrum (strain ATCC MYA-4607 / CBS 118892) (Athlete'sfoot fungus) | |||
16. | ALA4077246 | 7f | t1/2 | = | 16 | hr | ALA4056617 | hr | Mus musculus | |||
17. | ALA4077246 | 7f | t1/2 | = | 16 | hr | ALA4056616 | hr | Mus musculus | |||
18. | ALA4077246 | 7f | t1/2 | = | 16 | hr | ALA4056615 | hr | Mus musculus | |||
19. | ALA4077246 | 7f | Drug uptake | = | 65 | % | ALA4056614 | % | Mus musculus | |||
20. | ALA4077246 | 7f | Drug uptake | = | 58 | % | ALA4056613 | % | Mus musculus |