| # | Name | Compound Key | Action Type | Relation | Activity Value | Units | Assay ID | Assay Description | Comment | Assay | Assay Organism | |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1. |  ALA4079102 | 40 | F | = | 88 | % | ALA4037542 | % | Rattus norvegicus | |||
| 2. | ALA4079102 | 40 | AUC/dose | = | 961 | ng.hr/ml/mg/kg | ALA4037541 | ng.hr/ml/mg/kg | Rattus norvegicus | |||
| 3. | ALA4079102 | 40 | Cmax | = | 292 | ng/ml | ALA4037540 | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | nM | Rattus norvegicus | ||
| 4. | ALA4079102 | 40 | Tmax | = | 2.5 | hr | ALA4037539 | hr | Rattus norvegicus | |||
| 5. | ALA4079102 | 40 | AUC/dose | = | 1071 | ng.hr/ml/mg/kg | ALA4037538 | ng.hr/ml/mg/kg | Rattus norvegicus | |||
| 6. | ALA4079102 | 40 | beta t1/2 | = | 2.5 | hr | ALA4037537 | hr | Rattus norvegicus | |||
| 7. | ALA4079102 | 40 | Vdss | = | 2.2 | L/Kg | ALA4037536 | L.kg-1 | Rattus norvegicus | |||
| 8. | ALA4079102 | 40 | CL | = | 15.7 | ml/min.kg | ALA4037535 | mL.min-1.kg-1 | Rattus norvegicus | |||
| 9. | ALA4079102 | 40 | AUC/dose | = | 97 | ng.hr/g/mg/kg | ALA4037532 | ng.hr/g/mg/kg | Rattus norvegicus | |||
| 10. | ALA4079102 | 40 | Kp | = | 0.16 | ALA4037533 | ||||||
| 11. | ALA4079102 | 40 | Fu | = | 1.1 | % | ALA4037530 | Rattus norvegicus | ||||
| 12. | ALA4079102 | 40 | pIC50 | = | 7 | ALA4037528 | 7.00 | nM | Homo sapiens | |||
| 13. | ALA4079102 | 40 | Fu | = | 3.4 | % | ALA4037529 | Rattus norvegicus | ||||
| 14. | ALA4079102 | 40 | AUC/dose | = | 614 | ng.hr/ml/mg/kg | ALA4037531 | ng.hr/ml/mg/kg | Rattus norvegicus | |||
| 15. | ALA4079102 | 40 | K(p,uu,brain) | = | 0.48 | ALA4037534 | ||||||
| 16. | ALA4079102 | 40 | pIC50 | = | 9.2 | ALA4037524 | 9.20 | nM | Homo sapiens | |||
| 17. | ALA4079102 | 40 | solubility | = | 3 | ug ml-1 | ALA4037525 | ug.mL-1 | ||||
| 18. | ALA4079102 | 40 | Ratio | = | 0.87 | ALA4037526 | Canis lupus familiaris | |||||
| 19. | ALA4079102 | 40 | permeability | = | 654 | nm/s | ALA4037527 | nm/s | Canis lupus familiaris |
The page will load shortly, Thanks for your patience!