| # | Name | Compound Key | Action Type | Relation | Activity Value | Units | Assay ID | Assay Description | Comment | Assay | Assay Organism | |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1. |  ALA4079746 | 9m | TGI | 0 | ALA4023102 | Dose-dependent effect | Homo sapiens | |||||
| 2. | ALA4079746 | 9m | PPB | = | 64 | % | ALA4023128 | % | Homo sapiens | |||
| 3. | ALA4079746 | 9m | PPB | = | 60.1 | % | ALA4023127 | % | Oryctolagus cuniculus | |||
| 4. | ALA4079746 | 9m | t1/2 | = | 9.98 | hr | ALA4023126 | hr | Rattus norvegicus | |||
| 5. | ALA4079746 | 9m | t1/2 | = | 7.57 | hr | ALA4023125 | hr | Rattus norvegicus | |||
| 6. | ALA4079746 | 9m | CL | = | 3.51 | L/hr/kg | ALA4023124 | mL.min-1.kg-1 | Rattus norvegicus | |||
| 7. | ALA4079746 | 9m | CL | = | 1.53 | L/hr/kg | ALA4023123 | mL.min-1.kg-1 | Rattus norvegicus | |||
| 8. | ALA4079746 | 9m | Vdss(app) | = | 21.79 | L/Kg | ALA4023122 | L.kg-1 | Rattus norvegicus | |||
| 9. | ALA4079746 | 9m | Vdss | = | 16.66 | L/Kg | ALA4023121 | L.kg-1 | Rattus norvegicus | |||
| 10. | ALA4079746 | 9m | MRT | = | 16.31 | hr | ALA4023120 | hr | Rattus norvegicus | |||
| 11. | ALA4079746 | 9m | MRT | = | 11.64 | hr | ALA4023119 | hr | Rattus norvegicus | |||
| 12. | ALA4079746 | 9m | F | = | 43.5 | % | ALA4023118 | % | Rattus norvegicus | |||
| 13. | ALA4079746 | 9m | Tmax | = | 3 | hr | ALA4023117 | hr | Rattus norvegicus | |||
| 14. | ALA4079746 | 9m | Cmax | = | 807.24 | ug/L | ALA4023116 | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | nM | Rattus norvegicus | ||
| 15. | ALA4079746 | 9m | Cmax | = | 4473.47 | ug/L | ALA4023115 | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | nM | Rattus norvegicus | ||
| 16. | ALA4079746 | 9m | AUC | = | 2853.41 | ug/L.hr | ALA4023114 | ng.hr.mL-1 | Rattus norvegicus | |||
| 17. | ALA4079746 | 9m | AUC | = | 6558.52 | ug/L.hr | ALA4023113 | ng.hr.mL-1 | Rattus norvegicus | |||
| 18. | ALA4079746 | 9m | Activity | 0 | ALA4023112 | Non-Toxic | Mus musculus | |||||
| 19. | ALA4079746 | 9m | Activity | 0 | ALA4023111 | Dose-dependent effect | Mus musculus | |||||
| 20. | ALA4079746 | 9m | Activity | 0 | ALA4023110 | Dose-dependent effect | Mus musculus |
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