| # | Name | Compound Key | Action Type | Relation | Activity Value | Units | Assay ID | Assay Description | Comment | Assay | Assay Organism | |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1. |  ALA4080667 | 6n-1; Enantiomer-1 | Cmin | = | 80 | nM | ALA4016433 | nM | Macaca fascicularis | |||
| 2. | ALA4080667 | 6n-1; Enantiomer-1 | Ratio | = | 4 | ALA4016432 | ||||||
| 3. | ALA4080667 | 6n-1; Enantiomer-1 | Cp(f) | = | 2 | nM | ALA4016431 | nM | Macaca fascicularis | |||
| 4. | ALA4080667 | 6n-1; Enantiomer-1 | Cp | = | 6 | nM | ALA4016430 | nM | Macaca fascicularis | |||
| 5. | ALA4080667 | 6n-1; Enantiomer-1 | Activity | 0 | ALA4016429 | Non-Toxic | Macaca fascicularis | |||||
| 6. | ALA4080667 | 6n-1; Enantiomer-1 | Activity | 0 | ALA4016428 | Non-Toxic | Macaca fascicularis | |||||
| 7. | ALA4080667 | 6n-1; Enantiomer-1 | Activity | 0 | ALA4016427 | Non-Toxic | Macaca fascicularis | |||||
| 8. | ALA4080667 | 6n-1; Enantiomer-1 | Ratio AUC | = | 0.003 | ALA4016426 | Macaca fascicularis | |||||
| 9. | ALA4080667 | 6n-1; Enantiomer-1 | Ratio AUC | = | 0.2 | ALA4016425 | Canis lupus familiaris | |||||
| 10. | ALA4080667 | 6n-1; Enantiomer-1 | Ratio AUC | = | 0.02 | ALA4016422 | Rattus norvegicus | |||||
| 11. | ALA4080667 | 6n-1; Enantiomer-1 | Drug metabolism | 0 | ALA4016424 | Metabolite_Detected | Macaca fascicularis | |||||
| 12. | ALA4080667 | 6n-1; Enantiomer-1 | Drug metabolism | 0 | ALA4016423 | Metabolite_Detected | Canis lupus familiaris | |||||
| 13. | ALA4080667 | 6n-1; Enantiomer-1 | Drug metabolism | 0 | ALA4016421 | Metabolite_Detected | Rattus norvegicus | |||||
| 14. | ALA4080667 | 6n-1; Enantiomer-1 | EC50 | = | 0.075 | uM | ALA4016420 | 7.12 | nM | Macaca fascicularis | ||
| 15. | ALA4080667 | 6n-1; Enantiomer-1 | Tmax | = | 30 | min | ALA4016419 | hr | Macaca fascicularis | |||
| 16. | ALA4080667 | 6n-1; Enantiomer-1 | ED50 | = | 0.12 | mg kg-1 | ALA4016418 | mg.kg-1 | Macaca fascicularis | |||
| 17. | ALA4080667 | 6n-1; Enantiomer-1 | EC50 | = | 0.85 | uM | ALA4016417 | 6.07 | nM | Mus musculus | ||
| 18. | ALA4080667 | 6n-1; Enantiomer-1 | Drug uptake | 0 | ALA4016416 | Dose-dependent effect | Mus musculus | |||||
| 19. | ALA4080667 | 6n-1; Enantiomer-1 | INH | 0 | ALA4016334 | Dose-dependent effect | % | Mus musculus | ||||
| 20. | ALA4080667 | 6n-1; Enantiomer-1 | ED50 | = | 8.6 | mg kg-1 | ALA4016334 | mg.kg-1 | Mus musculus |
The page will load shortly, Thanks for your patience!