| # | Name | Compound Key | Action Type | Relation | Activity Value | Units | Assay ID | Assay Description | Comment | Assay | Assay Organism | |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1. |  ALA4082403 | 1 | IC50 | > | 300 | nM | ALA4012483 | nM | Homo sapiens | |||
| 2. | ALA4082403 | 1 | IC50 | = | 1.1 | nM | ALA4012483 | 8.96 | nM | Homo sapiens | ||
| 3. | ALA4082403 | 1 | IC50 | > | 100 | nM | ALA4012482 | nM | Mus musculus | |||
| 4. | ALA4082403 | 1 | IC50 | = | 0.73 | nM | ALA4012482 | 9.14 | nM | Mus musculus | ||
| 5. | ALA4082403 | 1 | IC50 | > | 100 | nM | ALA4012481 | nM | Homo sapiens | |||
| 6. | ALA4082403 | 1 | IC50 | = | 0.73 | nM | ALA4012481 | 9.14 | nM | Homo sapiens | ||
| 7. | ALA4082403 | 1 | INH | = | 4.1 | % | ALA4012480 | % | Homo sapiens | |||
| 8. | ALA4082403 | 1 | AUC | = | 3.3 | microg.hr/mL | ALA4012499 | ng.hr.mL-1 | Macaca fascicularis | |||
| 9. | ALA4082403 | 1 | Tmax | = | 2.67 | hr | ALA4012498 | hr | Macaca fascicularis | |||
| 10. | ALA4082403 | 1 | Cmax | = | 0.515 | ug ml-1 | ALA4012497 | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | nM | Macaca fascicularis | ||
| 11. | ALA4082403 | 1 | t1/2 | = | 2.31 | hr | ALA4012496 | hr | Macaca fascicularis | |||
| 12. | ALA4082403 | 1 | Activity | 0 | ALA4012494 | Active | Macaca fascicularis | |||||
| 13. | ALA4082403 | 1 | solubility | = | 260 | ug ml-1 | ALA4012493 | ug.mL-1 | ||||
| 14. | ALA4082403 | 1 | solubility | = | 860 | ug ml-1 | ALA4012479 | ug.mL-1 | ||||
| 15. | ALA4082403 | 1 | PPB | = | 81.5 | % | ALA4012492 | % | Mus musculus | |||
| 16. | ALA4082403 | 1 | Stability | = | 100 | % | ALA4012491 | % | Homo sapiens | |||
| 17. | ALA4082403 | 1 | INH | = | 16 | % | ALA4012490 | % | Homo sapiens | |||
| 18. | ALA4082403 | 1 | INH | = | 5.8 | % | ALA4012489 | % | Homo sapiens | |||
| 19. | ALA4082403 | 1 | INH | = | 3.4 | % | ALA4012488 | % | Homo sapiens | |||
| 20. | ALA4082403 | 1 | INH | < | 0 | % | ALA4012487 | % | Homo sapiens |
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