| # | Name | Compound Key | Action Type | Relation | Activity Value | Units | Assay ID | Assay Description | Comment | Assay | Assay Organism | |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1. |  ALA4082422 | 11; Tab 2, Entry 6 | Cmax | = | 292 | ng/ml | ALA4047378 | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | nM | Mus musculus | ||
| 2. | ALA4082422 | 11; Tab 2, Entry 6 | Vdss | = | 4.6 | L/Kg | ALA4047377 | L.kg-1 | Mus musculus | |||
| 3. | ALA4082422 | 11; Tab 2, Entry 6 | CL | = | 1.1 | L/hr/kg | ALA4047376 | mL.min-1.kg-1 | Mus musculus | |||
| 4. | ALA4082422 | 11; Tab 2, Entry 6 | F | = | 155 | % | ALA4047375 | % | Mus musculus | |||
| 5. | ALA4082422 | 11; Tab 2, Entry 6 | t1/2 | = | 8.9 | hr | ALA4047374 | hr | Mus musculus | |||
| 6. | ALA4082422 | 11; Tab 2, Entry 6 | t1/2 | = | 3.1 | hr | ALA4047373 | hr | Mus musculus | |||
| 7. | ALA4082422 | 11; Tab 2, Entry 6 | AUC | = | 13700 | ng.hr/ml | ALA4047372 | ng.hr.mL-1 | Mus musculus | |||
| 8. | ALA4082422 | 11; Tab 2, Entry 6 | IC50 | = | 0.115 | uM | ALA4047365 | 6.94 | nM | Homo sapiens | ||
| 9. | ALA4082422 | 11; Tab 2, Entry 6 | IC50 | = | 0.31 | uM | ALA4047361 | 6.51 | nM | Homo sapiens | ||
| 10. | ALA4082422 | 11; Tab 2, Entry 6 | permeability | = | 19 | 10'-7 cm/s | ALA4047366 | 10'-7 cm/s | Homo sapiens | |||
| 11. | ALA4082422 | 11; Tab 2, Entry 6 | IC50 | = | 2.9 | uM | ALA4047367 | 5.54 | nM | Homo sapiens | ||
| 12. | ALA4082422 | 11; Tab 2, Entry 6 | CLH | = | 2 | % | ALA4047368 | % | Homo sapiens | |||
| 13. | ALA4082422 | 11; Tab 2, Entry 6 | Therm_solubility | = | 0.4 | uM | ALA4047369 | nM | ||||
| 14. | ALA4082422 | 11; Tab 2, Entry 6 | INH | 0 | ALA4047370 | Not Active | % | |||||
| 15. | ALA4082422 | 11; Tab 2, Entry 6 | Activity | 0 | ALA4047371 | Not Active | ||||||
| 16. | ALA4082422 | 11; Tab 2, Entry 6 | IC50 | = | 0.001 | uM | ALA4047362 | 9.00 | nM | Homo sapiens | ||
| 17. | ALA4082422 | 11; Tab 2, Entry 6 | IC50 | = | 0.013 | uM | ALA4047363 | 7.89 | nM | Homo sapiens |
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