# | Name | Compound Key | Action Type | Relation | Activity Value | Units | Assay ID | Assay Description | Comment | Assay | Assay Organism | |
---|---|---|---|---|---|---|---|---|---|---|---|---|
1. | ALA4082978 | 20a | MED | = | 7.5 | mg kg-1 | ALA4005517 | mg kg-1 | Homo sapiens | |||
2. | ALA4082978 | 20a | TGI | = | 42 | % | ALA4005469 | % | Homo sapiens | |||
3. | ALA4082978 | 20a | TGI | = | 65 | % | ALA4005516 | % | Homo sapiens | |||
4. | ALA4082978 | 20a | TGI | = | 73 | % | ALA4005515 | % | Homo sapiens | |||
5. | ALA4082978 | 20a | GI50 | = | 80 | nM | ALA4005488 | nM | Homo sapiens | |||
6. | ALA4082978 | 20a | GI50 | = | 2 | nM | ALA4005487 | nM | Homo sapiens | |||
7. | ALA4082978 | 20a | GI50 | = | 12 | nM | ALA4005486 | nM | Homo sapiens | |||
8. | ALA4082978 | 20a | GI50 | = | 38 | nM | ALA4005485 | nM | Homo sapiens | |||
9. | ALA4082978 | 20a | GI50 | = | 120 | nM | ALA4005484 | nM | Homo sapiens | |||
10. | ALA4082978 | 20a | EC50 | = | 5.6 | nM | ALA4005483 | 8.25 | nM | |||
11. | ALA4082978 | 20a | EC50 | = | 3.4 | nM | ALA4005482 | 8.47 | nM | Homo sapiens | ||
12. | ALA4082978 | 20a | EC50 | = | 5.7 | nM | ALA4005481 | 8.24 | nM | Homo sapiens | ||
13. | ALA4082978 | 20a | EC50 | = | 7.3 | nM | ALA4005480 | 8.14 | nM | Homo sapiens | ||
14. | ALA4082978 | 20a | EC50 | = | 5.4 | nM | ALA4005479 | 8.27 | nM | Homo sapiens | ||
15. | ALA4082978 | 20a | MRT | = | 4.54 | hr | ALA4005514 | hr | Macaca mulatta | |||
16. | ALA4082978 | 20a | betat1/2(app) | = | 3.61 | hr | ALA4005513 | hr | Macaca mulatta | |||
17. | ALA4082978 | 20a | Vdss | = | 1.88 | L/Kg | ALA4005512 | L.kg-1 | Macaca mulatta | |||
18. | ALA4082978 | 20a | CL | = | 0.41 | L/hr/kg | ALA4005511 | mL.min-1.kg-1 | Macaca mulatta | |||
19. | ALA4082978 | 20a | Fu | = | 3.33 | % | ALA4005510 | Macaca mulatta | ||||
20. | ALA4082978 | 20a | F | = | 68.6 | % | ALA4005509 | % | Macaca fascicularis |