# | Name | Compound Key | Action Type | Relation | Activity Value | Units | Assay ID | Assay Description | Comment | Assay | Assay Organism | |
---|---|---|---|---|---|---|---|---|---|---|---|---|
1. | ALA4084182 | 4 | EC50 | = | 12.68 | uM | ALA4017717 | 4.90 | nM | Homo sapiens | ||
2. | ALA4084182 | 4 | BPR | = | 5 | ALA4017755 | ||||||
3. | ALA4084182 | 4 | t1/2 | > | 3 | hr | ALA4017754 | hr | Mus musculus | |||
4. | ALA4084182 | 4 | F | = | 56 | % | ALA4017753 | % | Mus musculus | |||
5. | ALA4084182 | 4 | PPB | = | 93.4 | % | ALA4017722 | % | Homo sapiens | |||
6. | ALA4084182 | 4 | PPB | = | 88.8 | % | ALA4017721 | % | Mus musculus | |||
7. | ALA4084182 | 4 | Activity | 0 | ALA4017720 | Active | Homo sapiens | |||||
8. | ALA4084182 | 4 | Ki | = | 38 | nM | ALA4017718 | 7.42 | nM | Homo sapiens | ||
9. | ALA4084182 | 4 | AUC | = | 480 | ng.hr/ml | ALA4017752 | ng.hr.mL-1 | Mus musculus | |||
10. | ALA4084182 | 4 | AUCt | = | 414 | ng.hr/ml | ALA4017751 | ng.hr.mL-1 | Mus musculus | |||
11. | ALA4084182 | 4 | Tmax | = | 1 | hr | ALA4017750 | hr | Mus musculus | |||
12. | ALA4084182 | 4 | Cmax | = | 674.3 | nM | ALA4017749 | nM | Mus musculus | |||
13. | ALA4084182 | 4 | t1/2 | > | 3 | hr | ALA4017748 | hr | Mus musculus | |||
14. | ALA4084182 | 4 | IC50 | = | 430 | nM | ALA4017747 | 6.37 | nM | Homo sapiens | ||
15. | ALA4084182 | 4 | IC50 | = | 216 | nM | ALA4017746 | 6.67 | nM | Homo sapiens | ||
16. | ALA4084182 | 4 | F | = | 40 | % | ALA4017716 | % | Mus musculus | |||
17. | ALA4084182 | 4 | AUC | = | 141 | ng.hr/ml | ALA4017745 | ng.hr.mL-1 | Mus musculus | |||
18. | ALA4084182 | 4 | AUCt | = | 119 | ng.hr/ml | ALA4017744 | ng.hr.mL-1 | Mus musculus | |||
19. | ALA4084182 | 4 | Tmax | = | 0.25 | hr | ALA4017743 | hr | Mus musculus | |||
20. | ALA4084182 | 4 | Cmax | = | 304.5 | nM | ALA4017742 | nM | Mus musculus |