# | Name | Compound Key | Action Type | Relation | Activity Value | Units | Assay ID | Assay Description | Comment | Assay | Assay Organism | |
---|---|---|---|---|---|---|---|---|---|---|---|---|
1. | T-3764518 | 1o; T-3764518 | Activity | 0 | ALA4055371 | Non-Toxic | Mus musculus | |||||
2. | T-3764518 | 1o; T-3764518 | T/C | = | 32.8 | % | ALA4055370 | % | Homo sapiens | |||
3. | T-3764518 | 1o; T-3764518 | INH | 0 | ALA4055369 | Active | % | Mus musculus | ||||
4. | T-3764518 | 1o; T-3764518 | Fu | = | 0.07 | ALA4055362 | Mus musculus | |||||
5. | T-3764518 | 1o; T-3764518 | MRT | = | 4.2 | hr | ALA4055368 | hr | Mus musculus | |||
6. | T-3764518 | 1o; T-3764518 | AUC | = | 3756.5 | ng.hr/ml | ALA4055367 | ng.hr.mL-1 | Mus musculus | |||
7. | T-3764518 | 1o; T-3764518 | CL | = | 310 | ml/hr/kg | ALA4055366 | mL.min-1.kg-1 | Mus musculus | |||
8. | T-3764518 | 1o; T-3764518 | Stability | = | 33 | microL/min/mg | ALA4055365 | microL/min/mg | Mus musculus | |||
9. | T-3764518 | 1o; T-3764518 | Stability | = | 14 | microL/min/mg | ALA4055364 | microL/min/mg | Homo sapiens | |||
10. | T-3764518 | 1o; T-3764518 | GI50 | = | 2.7 | nM | ALA4055363 | nM | Homo sapiens | |||
11. | T-3764518 | 1o; T-3764518 | IC50 | = | 4.7 | nM | ALA4055361 | 8.33 | nM | Homo sapiens |