# | Name | Compound Key | Action Type | Relation | Activity Value | Units | Assay ID | Assay Description | Comment | Assay | Assay Organism | |
---|---|---|---|---|---|---|---|---|---|---|---|---|
1. | ALA4086461 | (R)-11 | IC50 | > | 30 | uM | ALA4047384 | nM | Homo sapiens | |||
2. | ALA4086461 | (R)-11 | IC50 | > | 30 | uM | ALA4047383 | nM | Homo sapiens | |||
3. | ALA4086461 | (R)-11 | Stability | = | 11 | % | ALA4047382 | % | Mus musculus | |||
4. | ALA4086461 | (R)-11 | Stability | = | 8 | % | ALA4047381 | % | Rattus norvegicus | |||
5. | ALA4086461 | (R)-11 | Stability | = | 3 | % | ALA4047380 | % | Homo sapiens | |||
6. | ALA4086461 | (R)-11 | IC50 | = | 22 | nM | ALA4047363 | 7.66 | nM | Homo sapiens | ||
7. | ALA4086461 | (R)-11 | IC50 | = | 822 | nM | ALA4047361 | 6.08 | nM | Homo sapiens | ||
8. | ALA4086461 | (R)-11 | permeability | = | 36 | 10'-7 cm/s | ALA4047366 | 10'-7 cm/s | Homo sapiens | |||
9. | ALA4086461 | (R)-11 | IC50 | = | 1.5 | uM | ALA4047367 | 5.82 | nM | Homo sapiens | ||
10. | ALA4086461 | (R)-11 | Therm_solubility | 0 | ALA4047369 | Not Determined | ||||||
11. | ALA4086461 | (R)-11 | IC50 | = | 4 | nM | ALA4047362 | 8.40 | nM | Homo sapiens |