Activities

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Activities

Activities

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#	Name	Compound Key	Action Type	Relation	Activity Value	Units	Assay ID	Assay Description	Comment	Assay	Assay Organism
1.	ALA4086672	6a	ED99	=	3.8	mg kg-1	ALA4020362			mg kg-1	Mycobacterium tuberculosis
2.	ALA4086672	6a	F	=	72	%	ALA4020361			%	Mus musculus
3.	ALA4086672	6a	AUC/dose	=	0.84	hr.microg/ml	ALA4020360			hr.microg/ml	Mus musculus
4.	ALA4086672	6a	AUC	=	4.21	hr.microg/ml	ALA4020359			ng.hr.mL-1	Mus musculus
5.	ALA4086672	6a	Tmax	=	0.25	hr	ALA4020358			hr	Mus musculus
6.	ALA4086672	6a	Cmax	=	0.98	ug ml-1	ALA4020357		standard_value was converted from ug.mL-1 to nM using the parent compound MW \| standard_value was converted from ug.mL-1 to nM using the parent compound MW \| standard_value was converted from ug.mL-1 to nM using the parent compound MW \| standard_value was converted from ug.mL-1 to nM using the parent compound MW \| standard_value was converted from ug.mL-1 to nM using the parent compound MW \| standard_value was converted from ug.mL-1 to nM using the parent compound MW	nM	Mus musculus
7.	ALA4086672	6a	AUC/dose	=	1.17	ug.hr/mL/mg/kg	ALA4020356			ug.hr/mL/mg/kg	Mus musculus
8.	ALA4086672	6a	AUC	=	5.84	hr.microg/ml	ALA4020355			ng.hr.mL-1	Mus musculus
9.	ALA4086672	6a	t1/2	=	2.4	hr	ALA4020354			hr	Mus musculus
10.	ALA4086672	6a	CL	=	14.2	ml/min.kg	ALA4020353			mL.min-1.kg-1	Mus musculus
11.	ALA4086672	6a	Vdss	=	2.5	L/Kg	ALA4020352			L.kg-1	Mus musculus
12.	ALA4086672	6a	Selectivity Index	=	970		ALA4020314
13.	ALA4086672	6a	EC50	=	74.5	uM	ALA4020317	4.13		nM	Homo sapiens
14.	ALA4086672	6a	EC50	=	97	uM	ALA4020316	4.01		nM	Homo sapiens
15.	ALA4086672	6a	IC50	>	300	uM	ALA4020315			nM	Homo sapiens
16.	ALA4086672	6a	IC50	>	300	uM	ALA4020313			nM	Homo sapiens
17.	ALA4086672	6a	MIC	=	0.1	uM	ALA4020312			nM	Mycobacterium tuberculosis
18.	ALA4086672	6a	IC50	=	0.074	uM	ALA4020311	7.13		nM	Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)