| # | Name | Compound Key | Action Type | Relation | Activity Value | Units | Assay ID | Assay Description | Comment | Assay | Assay Organism | |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1. |  ALA4088716 | (S)-27 | F | = | 100 | % | ALA5227331 | % | ||||
| 2. | ALA4088716 | (S)-27 | solubility | = | 73 | ug ml-1 | ALA5227329 | ug.mL-1 | ||||
| 3. | ALA4088716 | (S)-27 | IC50 | = | 1 | nM | ALA5227328 | 9.00 | nM | Mus musculus | ||
| 4. | ALA4088716 | (S)-27 | AUClast | = | 12266 | ng.hr/ml | ALA4000314 | ng.hr.mL-1 | Mus musculus | |||
| 5. | ALA4088716 | (S)-27 | t1/2 | = | 1.9 | hr | ALA4000313 | hr | Mus musculus | |||
| 6. | ALA4088716 | (S)-27 | Cmax | = | 4268 | ng/ml | ALA4000312 | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | nM | Mus musculus | ||
| 7. | ALA4088716 | (S)-27 | F | = | 106 | % | ALA4000311 | % | Mus musculus | |||
| 8. | ALA4088716 | (S)-27 | INH | 0 | ALA4000295 | Dose-dependent effect | % | Homo sapiens | ||||
| 9. | ALA4088716 | (S)-27 | TGI | 0 | ALA4000310 | Dose-dependent effect | Mus musculus | |||||
| 10. | ALA4088716 | (S)-27 | TGI | = | 91 | % | ALA4000309 | % | Mus musculus | |||
| 11. | ALA4088716 | (S)-27 | TGI | = | 71 | % | ALA4000308 | % | Mus musculus | |||
| 12. | ALA4088716 | (S)-27 | TGI | = | 50 | % | ALA4000307 | % | Mus musculus | |||
| 13. | ALA4088716 | (S)-27 | INH | 0 | ALA4000306 | Active | % | Mus musculus | ||||
| 14. | ALA4088716 | (S)-27 | INH | 0 | ALA4000305 | Active | % | Homo sapiens | ||||
| 15. | ALA4088716 | (S)-27 | CLH | = | 8 | microL/min/mg | ALA4000304 | mL.min-1.g-1 | Mus musculus | |||
| 16. | ALA4088716 | (S)-27 | IC50 | = | 8 | uM | ALA4000302 | 5.10 | nM | Homo sapiens | ||
| 17. | ALA4088716 | (S)-27 | IC50 | > | 20 | uM | ALA4000301 | nM | Homo sapiens | |||
| 18. | ALA4088716 | (S)-27 | permeability | = | 50.6 | ucm/s | ALA4000300 | ucm/s | ||||
| 19. | ALA4088716 | (S)-27 | IC50 | = | 0.001 | uM | ALA4000296 | 9.00 | nM | Homo sapiens | ||
| 20. | ALA4088716 | (S)-27 | Therm_solubility | = | 72.5 | ug ml-1 | ALA4000299 | ug.mL-1 |
The page will load shortly, Thanks for your patience!