# | Name | Compound Key | Action Type | Relation | Activity Value | Units | Assay ID | Assay Description | Comment | Assay | Assay Organism | |
---|---|---|---|---|---|---|---|---|---|---|---|---|
1. | PROTAC RIPK degrader-2 | 3 | pIC50 | = | 7 | ALA4832928 | 7.00 | nM | Homo sapiens | |||
2. | PROTAC RIPK degrader-2 | 3 | pIC50 | = | 7 | ALA4832927 | 7.00 | nM | Homo sapiens | |||
3. | PROTAC RIPK degrader-2 | 3 | DC50 | = | 1.5 | nM | ALA4832924 | nM | Homo sapiens | |||
4. | PROTAC RIPK degrader-2 | 3 | DC50 | = | 1 | nM | ALA4026936 | nM | Homo sapiens | |||
5. | PROTAC RIPK degrader-2 | 3 | Kd | = | 0.5 | uM | ALA4026935 | 6.30 | nM | Homo sapiens | ||
6. | PROTAC RIPK degrader-2 | 3 | Emax | > | 95 | % | ALA4388599 | % | Homo sapiens | |||
7. | PROTAC RIPK degrader-2 | 3 | DC50 | = | 1.4 | nM | ALA4388598 | nM | Homo sapiens | |||
8. | PROTAC RIPK degrader-2 | 3 | Emax | > | 95 | % | ALA4349406 | % | Homo sapiens | |||
9. | PROTAC RIPK degrader-2 | 3 | IC50 | = | 656 | nM | ALA4349408 | 6.18 | nM | Homo sapiens | ||
10. | PROTAC RIPK degrader-2 | 3 | DC50 | = | 1.4 | nM | ALA4349407 | nM | Homo sapiens | |||
11. | PROTAC RIPK degrader-2 | 3 | Emax | > | 95 | % | ALA5137719 | % | Homo sapiens | |||
12. | PROTAC RIPK degrader-2 | 3 | DC50 | = | 1.4 | nM | ALA5137718 | nM | Homo sapiens |