# | Name | Compound Key | Action Type | Relation | Activity Value | Units | Assay ID | Assay Description | Comment | Assay | Assay Organism | |
---|---|---|---|---|---|---|---|---|---|---|---|---|
1. | ALA4098876 | 12 | IC50 | = | 0.006 | uM | ALA4041133 | 8.22 | nM | Homo sapiens | ||
2. | ALA4098876 | 12 | EC50 | = | 0.589 | uM | ALA4041134 | 6.23 | nM | Homo sapiens | ||
3. | ALA4098876 | 12 | solubility | = | 19 | uM | ALA4041135 | nM | ||||
4. | ALA4098876 | 12 | t1/2 | = | 15 | min | ALA4041136 | hr | Rattus norvegicus | |||
5. | ALA4098876 | 12 | CL | = | 24 | ml/min.kg | ALA4041137 | mL.min-1.kg-1 | Rattus norvegicus | |||
6. | ALA4098876 | 12 | AUC | = | 811 | nM.hr | ALA4041138 | standard_value was converted from uM.hr to ng.hr.mL-1 using the parent compound MW | standard_value was converted from uM.hr to ug.hr.mL-1 using the parent compound MW | standard_value was converted from uM.hr to ug.hr.mL-1 using the parent compound MW | standard_value was converted from uM.hr to ug.hr.mL-1 using the parent compound MW | standard_value was converted from uM.hr to ug.hr.mL-1 using the parent compound MW | standard_value was converted from uM.hr to ug.hr.mL-1 using the parent compound MW | ng.hr.mL-1 | Rattus norvegicus | ||
7. | ALA4098876 | 12 | Cmax | = | 308 | nM | ALA4041139 | nM | Rattus norvegicus | |||
8. | ALA4098876 | 12 | F | = | 45 | % | ALA4041140 | % | Rattus norvegicus | |||
9. | ALA4098876 | 12 | Activity | 0 | ALA4041146 | Dose-dependent effect | Mus musculus | |||||
10. | ALA4098876 | 12 | Ratio | = | 3 | ALA4041147 | ||||||
11. | ALA4098876 | 12 | Cp | >= | 2 | uM | ALA4041148 | uM | Mus musculus | |||
12. | ALA4098876 | 12 | Activity | 0 | ALA4041150 | Dose-dependent effect | Rattus norvegicus | |||||
13. | ALA4098876 | 12 | Activity | 0 | ALA4041151 | Dose-dependent effect | Rattus norvegicus | |||||
14. | ALA4098876 | 12 | Activity | 0 | ALA4041152 | Dose-dependent effect | Rattus norvegicus | |||||
15. | ALA4098876 | 12 | Activity | 0 | ALA4041154 | Active | Rattus norvegicus | |||||
16. | ALA4098876 | 12 | Activity | 0 | ALA4041155 | Active | Rattus norvegicus | |||||
17. | ALA4098876 | 12 | Activity | 0 | ALA4041156 | Active | Rattus norvegicus | |||||
18. | ALA4098876 | 12 | Activity | 0 | ALA4041157 | Active | Rattus norvegicus | |||||
19. | ALA4098876 | 12 | Activity | 0 | ALA4041158 | Dose-dependent effect | Mus musculus | |||||
20. | ALA4098876 | 12 | Cp | = | 10 | uM | ALA4041160 | uM | Mus musculus |