# | Name | Compound Key | Action Type | Relation | Activity Value | Units | Assay ID | Assay Description | Comment | Assay | Assay Organism | |
---|---|---|---|---|---|---|---|---|---|---|---|---|
1. | ALA4099048 | 35 | Papp | = | 4 | 10'-6 cm/s | ALA4022983 | 10'-6 cm/s | Canis lupus familiaris | |||
2. | ALA4099048 | 35 | solubility | = | 259 | uM | ALA4022982 | nM | ||||
3. | ALA4099048 | 35 | F | = | 61.1 | % | ALA4022981 | % | Rattus norvegicus | |||
4. | ALA4099048 | 35 | t1/2 | = | 1.3 | hr | ALA4022980 | hr | Rattus norvegicus | |||
5. | ALA4099048 | 35 | Vdss | = | 1.42 | L/Kg | ALA4022979 | L.kg-1 | Rattus norvegicus | |||
6. | ALA4099048 | 35 | CL | = | 56.4 | ml/min.kg | ALA4022978 | mL.min-1.kg-1 | Rattus norvegicus | |||
7. | ALA4099048 | 35 | IC50 | > | 200 | uM | ALA4022977 | nM | Homo sapiens | |||
8. | ALA4099048 | 35 | IC50 | >= | 8 | uM | ALA4022976 | nM | Homo sapiens | |||
9. | ALA4099048 | 35 | logD | = | 1.4 | ALA4022975 | ||||||
10. | ALA4099048 | 35 | CLH(app) | < | 8 | microL/min/mg | ALA4022974 | mL.min-1.g-1 | Homo sapiens | |||
11. | ALA4099048 | 35 | IC50 | > | 6.93 | uM | ALA4022973 | nM | Homo sapiens | |||
12. | ALA4099048 | 35 | IC50 | = | 0.216 | uM | ALA4022972 | 6.67 | nM | Homo sapiens | ||
13. | ALA4099048 | 35 | Ratio IC50 | = | 63 | ALA4022971 | ||||||
14. | ALA4099048 | 35 | IC50 | = | 0.939 | uM | ALA4022970 | 6.03 | nM | Homo sapiens | ||
15. | ALA4099048 | 35 | IC50 | = | 0.015 | uM | ALA4022969 | 7.82 | nM | Homo sapiens |