Activities

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Activities

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#	Name	Compound Key	Action Type	Relation	Activity Value	Units	Assay ID	Assay Description	Comment	Assay	Assay Organism
1.	ALA4099851	4j; AAT-008	logD	=	1.5		ALA3997162
2.	ALA4099851	4j; AAT-008	logD	=	0.7		ALA3997163
3.	ALA4099851	4j; AAT-008	logD	=	3.8		ALA3997164
4.	ALA4099851	4j; AAT-008	solubility	=	0.29	ug ml-1	ALA3997165			ug.mL-1
5.	ALA4099851	4j; AAT-008	solubility	=	4.3	ug ml-1	ALA3997166			ug.mL-1
6.	ALA4099851	4j; AAT-008	Ki	>	6000	nM	ALA3997117			nM	Homo sapiens
7.	ALA4099851	4j; AAT-008	Ki	=	1836	nM	ALA3997116	5.74		nM	Homo sapiens
8.	ALA4099851	4j; AAT-008	Ki	>	6000	nM	ALA3997115			nM	Homo sapiens
9.	ALA4099851	4j; AAT-008	Ki	=	0.97	nM	ALA3997110	9.01		nM	Homo sapiens
10.	ALA4099851	4j; AAT-008	pA2	=	8.97		ALA3997107	8.97		nM	Homo sapiens
11.	ALA4099851	4j; AAT-008	A2	=	1.1	nM	ALA3997107			nM	Homo sapiens
12.	ALA4099851	4j; AAT-008	INH	<	5	%	ALA3997161			%
13.	ALA4099851	4j; AAT-008	INH	<	5	%	ALA3997160			%	Homo sapiens
14.	ALA4099851	4j; AAT-008	INH	<	5	%	ALA3997159			%	Homo sapiens
15.	ALA4099851	4j; AAT-008	INH	<	5	%	ALA3997158			%	Homo sapiens
16.	ALA4099851	4j; AAT-008	INH	<	5	%	ALA3997157			%
17.	ALA4099851	4j; AAT-008	t1/2	>	360	min	ALA3997155			hr
18.	ALA4099851	4j; AAT-008	INH		0		ALA3997156		Dose-dependent effect	%	Rattus norvegicus
19.	ALA4099851	4j; AAT-008	MED	=	1	mg kg-1	ALA3997156			mg kg-1	Rattus norvegicus
20.	ALA4099851	4j; AAT-008	beta t1/2	=	21.9	hr	ALA3997154			hr	Macaca fascicularis