| # | Name | Compound Key | Action Type | Relation | Activity Value | Units | Assay ID | Assay Description | Comment | Assay | Assay Organism | |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1. |  ALA4100435 | 12; Tab 2, Entry 5 | CL | > | 75 | % | ALA4047379 | % | Mus musculus | |||
| 2. | ALA4100435 | 12; Tab 2, Entry 5 | Cmax | = | 958 | ng/ml | ALA4047378 | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | nM | Mus musculus | ||
| 3. | ALA4100435 | 12; Tab 2, Entry 5 | Vdss | = | 11 | L/Kg | ALA4047377 | L.kg-1 | Mus musculus | |||
| 4. | ALA4100435 | 12; Tab 2, Entry 5 | CL | = | 3.9 | L/hr/kg | ALA4047376 | mL.min-1.kg-1 | Mus musculus | |||
| 5. | ALA4100435 | 12; Tab 2, Entry 5 | F | = | 97 | % | ALA4047375 | % | Mus musculus | |||
| 6. | ALA4100435 | 12; Tab 2, Entry 5 | t1/2 | = | 3.3 | hr | ALA4047374 | hr | Mus musculus | |||
| 7. | ALA4100435 | 12; Tab 2, Entry 5 | t1/2 | = | 2.6 | hr | ALA4047373 | hr | Mus musculus | |||
| 8. | ALA4100435 | 12; Tab 2, Entry 5 | AUC | = | 2500 | ng.hr/ml | ALA4047372 | ng.hr.mL-1 | Mus musculus | |||
| 9. | ALA4100435 | 12; Tab 2, Entry 5 | IC50 | = | 0.075 | uM | ALA4047365 | 7.12 | nM | Homo sapiens | ||
| 10. | ALA4100435 | 12; Tab 2, Entry 5 | IC50 | = | 0.167 | uM | ALA4047361 | 6.78 | nM | Homo sapiens | ||
| 11. | ALA4100435 | 12; Tab 2, Entry 5 | permeability | = | 30 | 10'-7 cm/s | ALA4047366 | 10'-7 cm/s | Homo sapiens | |||
| 12. | ALA4100435 | 12; Tab 2, Entry 5 | IC50 | = | 1 | uM | ALA4047367 | 6.00 | nM | Homo sapiens | ||
| 13. | ALA4100435 | 12; Tab 2, Entry 5 | CLH | = | 21 | % | ALA4047368 | % | Homo sapiens | |||
| 14. | ALA4100435 | 12; Tab 2, Entry 5 | Therm_solubility | = | 13 | uM | ALA4047369 | nM | ||||
| 15. | ALA4100435 | 12; Tab 2, Entry 5 | IC50 | = | 0.001 | uM | ALA4047362 | 9.15 | nM | Homo sapiens | ||
| 16. | ALA4100435 | 12; Tab 2, Entry 5 | IC50 | = | 0.006 | uM | ALA4047363 | 8.22 | nM | Homo sapiens |
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