# | Name | Compound Key | Action Type | Relation | Activity Value | Units | Assay ID | Assay Description | Comment | Assay | Assay Organism | |
---|---|---|---|---|---|---|---|---|---|---|---|---|
1. | ALA4101680 | 33 | Drug uptake | = | 11 | nM | ALA4036839 | nM | Rattus norvegicus | |||
2. | ALA4101680 | 33 | Activity | 0 | ALA4036837 | Active | Rattus norvegicus | |||||
3. | ALA4101680 | 33 | Activity | 0 | ALA4036836 | Dose-dependent effect | Rattus norvegicus | |||||
4. | ALA4101680 | 33 | MED | = | 100 | mg kg-1 | ALA4036836 | mg kg-1 | Rattus norvegicus | |||
5. | ALA4101680 | 33 | Selectivity ratio | > | 100 | ALA4036835 | ||||||
6. | ALA4101680 | 33 | Selectivity ratio | > | 100 | ALA4036834 | ||||||
7. | ALA4101680 | 33 | Selectivity ratio | > | 100 | ALA4036833 | ||||||
8. | ALA4101680 | 33 | Selectivity ratio | > | 100 | ALA4036832 | ||||||
9. | ALA4101680 | 33 | IC50 | = | 0.195 | uM | ALA4036831 | 6.71 | nM | Rattus norvegicus | ||
10. | ALA4101680 | 33 | EC50 | > | 10 | uM | ALA4036829 | nM | Homo sapiens | |||
11. | ALA4101680 | 33 | IC50 | > | 30 | uM | ALA4036828 | nM | Homo sapiens | |||
12. | ALA4101680 | 33 | IC50 | = | 17700 | nM | ALA4036827 | 4.75 | nM | Homo sapiens | ||
13. | ALA4101680 | 33 | IC50 | = | 17300 | nM | ALA4036826 | 4.76 | nM | Homo sapiens | ||
14. | ALA4101680 | 33 | IC50 | > | 30 | uM | ALA4036825 | nM | Homo sapiens | |||
15. | ALA4101680 | 33 | IC50 | > | 10 | uM | ALA4036824 | nM | Homo sapiens | |||
16. | ALA4101680 | 33 | solubility | = | 4.8 | ug ml-1 | ALA4036823 | ug.mL-1 | ||||
17. | ALA4101680 | 33 | Ratio | < | 0.1 | ALA4036822 | Canis lupus familiaris | |||||
18. | ALA4101680 | 33 | permeability | = | 8 | 10'-6 cm/s | ALA4036820 | 10'-6 cm/s | Canis lupus familiaris | |||
19. | ALA4101680 | 33 | permeability | = | 4 | 10'-6 cm/s | ALA4036821 | 10'-6 cm/s | Canis lupus familiaris | |||
20. | ALA4101680 | 33 | CLH | = | 58 | microL/min/mg | ALA4036819 | mL.min-1.g-1 | Rattus norvegicus |