# | Name | Compound Key | Action Type | Relation | Activity Value | Units | Assay ID | Assay Description | Comment | Assay | Assay Organism | |
---|---|---|---|---|---|---|---|---|---|---|---|---|
1. | ALA4103356 | 44 | AUC | = | 1244 | ng.hr/ml | ALA4040043 | ng.hr.mL-1 | Mus musculus | |||
2. | ALA4103356 | 44 | CL | = | 4 | L/hr/kg | ALA4040042 | mL.min-1.kg-1 | Mus musculus | |||
3. | ALA4103356 | 44 | beta t1/2 | = | 2.1 | hr | ALA4040041 | hr | Mus musculus | |||
4. | ALA4103356 | 44 | Tmax | = | 0.5 | hr | ALA4040040 | hr | Mus musculus | |||
5. | ALA4103356 | 44 | Cmax | = | 1189 | ng/ml | ALA4040039 | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | nM | Mus musculus | ||
6. | ALA4103356 | 44 | PPB | = | 98.1 | % | ALA4040038 | % | ||||
7. | ALA4103356 | 44 | CLH | = | 23 | microL/min/mg | ALA4040037 | mL.min-1.g-1 | Homo sapiens | |||
8. | ALA4103356 | 44 | CLH | = | 15 | microL/min/mg | ALA4040036 | mL.min-1.g-1 | Mus musculus | |||
9. | ALA4103356 | 44 | IC50 | = | 8 | uM | ALA4040035 | 5.10 | nM | Homo sapiens | ||
10. | ALA4103356 | 44 | IC50 | > | 30 | uM | ALA4040034 | nM | Homo sapiens | |||
11. | ALA4103356 | 44 | Therm_solubility | > | 41 | ug ml-1 | ALA4040029 | ug.mL-1 | ||||
12. | ALA4103356 | 44 | Therm_solubility | = | 11.1 | ug ml-1 | ALA4040033 | ug.mL-1 | ||||
13. | ALA4103356 | 44 | IC50 | = | 0.012 | uM | ALA4040031 | 7.92 | nM | Homo sapiens |