# | Name | Compound Key | Action Type | Relation | Activity Value | Units | Assay ID | Assay Description | Comment | Assay | Assay Organism | |
---|---|---|---|---|---|---|---|---|---|---|---|---|
1. | ALA4104257 | 39 | AUC | = | 4948 | ng.hr/ml | ALA4040043 | ng.hr.mL-1 | Mus musculus | |||
2. | ALA4104257 | 39 | CL | = | 1.01 | L/hr/kg | ALA4040042 | mL.min-1.kg-1 | Mus musculus | |||
3. | ALA4104257 | 39 | beta t1/2 | = | 1.32 | hr | ALA4040041 | hr | Mus musculus | |||
4. | ALA4104257 | 39 | Tmax | = | 2 | hr | ALA4040040 | hr | Mus musculus | |||
5. | ALA4104257 | 39 | Cmax | = | 759 | ng/ml | ALA4040039 | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | nM | Mus musculus | ||
6. | ALA4104257 | 39 | PPB | = | 95 | % | ALA4040038 | % | ||||
7. | ALA4104257 | 39 | CLH | = | 7 | microL/min/mg | ALA4040037 | mL.min-1.g-1 | Homo sapiens | |||
8. | ALA4104257 | 39 | CLH | = | 12 | microL/min/mg | ALA4040036 | mL.min-1.g-1 | Mus musculus | |||
9. | ALA4104257 | 39 | IC50 | = | 6.2 | uM | ALA4040035 | 5.21 | nM | Homo sapiens | ||
10. | ALA4104257 | 39 | IC50 | > | 20 | uM | ALA4040034 | nM | Homo sapiens | |||
11. | ALA4104257 | 39 | Therm_solubility | = | 13.9 | ug ml-1 | ALA4040029 | ug.mL-1 | ||||
12. | ALA4104257 | 39 | Therm_solubility | = | 9.5 | ug ml-1 | ALA4040033 | ug.mL-1 | ||||
13. | ALA4104257 | 39 | IC50 | = | 0.029 | uM | ALA4040031 | 7.54 | nM | Homo sapiens |