| # | Name | Compound Key | Action Type | Relation | Activity Value | Units | Assay ID | Assay Description | Comment | Assay | Assay Organism | |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1. |  CDK8-IN-1 | 16 | F | = | 57.5 | % | ALA4046126 | % | Mus musculus | |||
| 2. | CDK8-IN-1 | 16 | Vdss | = | 0.49 | L/Kg | ALA4046125 | L.kg-1 | Mus musculus | |||
| 3. | CDK8-IN-1 | 16 | t1/2 | = | 7.91 | hr | ALA4046124 | hr | Mus musculus | |||
| 4. | CDK8-IN-1 | 16 | t1/2 | = | 0.84 | hr | ALA4046123 | hr | Mus musculus | |||
| 5. | CDK8-IN-1 | 16 | Tmax | = | 0.25 | hr | ALA4046122 | hr | Mus musculus | |||
| 6. | CDK8-IN-1 | 16 | Cmax | = | 12740 | ug/L | ALA4046121 | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | nM | Mus musculus | ||
| 7. | CDK8-IN-1 | 16 | Cmax | = | 9940 | ug/L | ALA4046120 | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | nM | Mus musculus | ||
| 8. | CDK8-IN-1 | 16 | CL | = | 8.87 | ml/min.kg | ALA4046119 | mL.min-1.kg-1 | Mus musculus | |||
| 9. | CDK8-IN-1 | 16 | IC50 | = | 0.003 | uM | ALA4046118 | 8.52 | nM | Homo sapiens | ||
| 10. | CDK8-IN-1 | 16 | IC50 | = | 0.27 | uM | ALA4046117 | 6.57 | nM | Homo sapiens |
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