| # | Name | Compound Key | Action Type | Relation | Activity Value | Units | Assay ID | Assay Description | Comment | Assay | Assay Organism | |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1. |  ALA4105032 | 10; PF-06679142 | Drug recovery | = | 2.2 | %ID | ALA4023945 | %ID | ||||
| 2. | ALA4105032 | 10; PF-06679142 | Ratio | = | 2.3 | ALA4023969 | Rattus norvegicus | |||||
| 3. | ALA4105032 | 10; PF-06679142 | Therm_solubility | = | 14 | uM | ALA4023961 | nM | ||||
| 4. | ALA4105032 | 10; PF-06679142 | Activity | 0 | ALA4023987 | Active | Homo sapiens | |||||
| 5. | ALA4105032 | 10; PF-06679142 | Activity | 0 | ALA4023990 | Active | Homo sapiens | |||||
| 6. | ALA4105032 | 10; PF-06679142 | Activity | 0 | ALA4023989 | Active | Homo sapiens | |||||
| 7. | ALA4105032 | 10; PF-06679142 | Activity | 0 | ALA4023988 | Active | Homo sapiens | |||||
| 8. | ALA4105032 | 10; PF-06679142 | F | = | 85 | % | ALA4023986 | % | Macaca fascicularis | |||
| 9. | ALA4105032 | 10; PF-06679142 | F | = | 26 | % | ALA4023985 | % | Rattus norvegicus | |||
| 10. | ALA4105032 | 10; PF-06679142 | AUC | = | 91600 | ng.hr/ml | ALA4023984 | ng.hr.mL-1 | Macaca fascicularis | |||
| 11. | ALA4105032 | 10; PF-06679142 | AUC | = | 35900 | ng.hr/ml | ALA4023983 | ng.hr.mL-1 | Macaca fascicularis | |||
| 12. | ALA4105032 | 10; PF-06679142 | AUC | = | 12800 | ng.hr/ml | ALA4023982 | ng.hr.mL-1 | Rattus norvegicus | |||
| 13. | ALA4105032 | 10; PF-06679142 | AUC | = | 16400 | ng.hr/ml | ALA4023981 | ng.hr.mL-1 | Rattus norvegicus | |||
| 14. | ALA4105032 | 10; PF-06679142 | Tmax | = | 2 | hr | ALA4023980 | hr | Macaca fascicularis | |||
| 15. | ALA4105032 | 10; PF-06679142 | Tmax | = | 2.7 | hr | ALA4023979 | hr | Rattus norvegicus | |||
| 16. | ALA4105032 | 10; PF-06679142 | Cmax | = | 8180 | ng/ml | ALA4023978 | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | nM | Macaca fascicularis | ||
| 17. | ALA4105032 | 10; PF-06679142 | Cmax | = | 1890 | ng/ml | ALA4023977 | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | nM | Rattus norvegicus | ||
| 18. | ALA4105032 | 10; PF-06679142 | t1/2 | = | 12 | hr | ALA4023976 | hr | Macaca fascicularis | |||
| 19. | ALA4105032 | 10; PF-06679142 | t1/2 | = | 4.95 | hr | ALA4023975 | hr | Rattus norvegicus | |||
| 20. | ALA4105032 | 10; PF-06679142 | Vdss | = | 0.3 | L/Kg | ALA4023974 | L.kg-1 | Macaca fascicularis |
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