| # | Name | Compound Key | Action Type | Relation | Activity Value | Units | Assay ID | Assay Description | Comment | Assay | Assay Organism | |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1. |  ALA4105269 | 35a | ED99 | = | 70 | mg kg-1 | ALA4020362 | mg kg-1 | Mycobacterium tuberculosis | |||
| 2. | ALA4105269 | 35a | AUC/dose | = | 2.54 | ug.hr/mL/mg/kg | ALA4020310 | ug.hr/mL/mg/kg | Mus musculus | |||
| 3. | ALA4105269 | 35a | AUC | = | 76.32 | hr.microg/ml | ALA4020341 | ng.hr.mL-1 | Mus musculus | |||
| 4. | ALA4105269 | 35a | t1/2 | = | 2.9 | hr | ALA4020340 | hr | Mus musculus | |||
| 5. | ALA4105269 | 35a | CL | = | 6.6 | ml/min.kg | ALA4020339 | mL.min-1.kg-1 | Mus musculus | |||
| 6. | ALA4105269 | 35a | F | = | 50 | % | ALA4020338 | % | Mus musculus | |||
| 7. | ALA4105269 | 35a | Vdss | = | 1.5 | L/Kg | ALA4020337 | L.kg-1 | Mus musculus | |||
| 8. | ALA4105269 | 35a | AUC/dose | = | 1.26 | hr.microg/ml | ALA4020336 | hr.microg/ml | Mus musculus | |||
| 9. | ALA4105269 | 35a | AUC | = | 37.67 | hr.microg/ml | ALA4020335 | ng.hr.mL-1 | Mus musculus | |||
| 10. | ALA4105269 | 35a | Tmax | = | 1 | hr | ALA4020334 | hr | Mus musculus | |||
| 11. | ALA4105269 | 35a | Cmax | = | 6.21 | ug ml-1 | ALA4020333 | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | nM | Mus musculus | ||
| 12. | ALA4105269 | 35a | Selectivity Index | = | 1035 | ALA4020314 | ||||||
| 13. | ALA4105269 | 35a | EC50 | = | 69.5 | uM | ALA4020317 | 4.16 | nM | Homo sapiens | ||
| 14. | ALA4105269 | 35a | EC50 | = | 82.8 | uM | ALA4020316 | 4.08 | nM | Homo sapiens | ||
| 15. | ALA4105269 | 35a | IC50 | 0 | ALA4020315 | Not Determined | Homo sapiens | |||||
| 16. | ALA4105269 | 35a | IC50 | = | 96.6 | uM | ALA4020313 | 4.01 | nM | Homo sapiens | ||
| 17. | ALA4105269 | 35a | MIC | = | 0.08 | uM | ALA4020312 | nM | Mycobacterium tuberculosis | |||
| 18. | ALA4105269 | 35a | IC50 | = | 0.046 | uM | ALA4020311 | 7.34 | nM | Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv) |
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