Activities

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Activities

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#	Name	Compound Key	Action Type	Relation	Activity Value	Units	Assay ID	Assay Description	Comment	Assay	Assay Organism
1.	ALA4105671	7b; 7b-m1	Activity		0		ALA4016655		Active		Homo sapiens
2.	ALA4105671	7b; 7b-m1	EC50	=	0.25	nM	ALA4016662	9.60		nM	Homo sapiens
3.	ALA4105671	7b; 7b-m1	Activity		0		ALA4016663		Not Active		Homo sapiens
4.	ALA4105671	7b; 7b-m1	Selectivity ratio	<=	1000		ALA4016664
5.	ALA4105671	7b; 7b-m1	t1/2	<	10	min	ALA4016665			hr	Rattus norvegicus
6.	ALA4105671	7b; 7b-m1	t1/2	<	10	min	ALA4016666			hr	Homo sapiens
7.	ALA4105671	7b; 7b-m1	Drug recovery	=	52	%	ALA4016667			%	Rattus norvegicus
8.	ALA4105671	7b; 7b-m1	Drug recovery	=	45	%	ALA4016668			%	Homo sapiens
9.	ALA4105671	7b; 7b-m1	Drug metabolism		0		ALA4016670		Metabolite_Detected		Homo sapiens
10.	ALA4105671	7b; 7b-m1	AUC	=	653	min.ug/ml	ALA4016671			ng.hr.mL-1	Rattus norvegicus
11.	ALA4105671	7b; 7b-m1	CL	=	1.55	ml/min	ALA4016672			ml/min	Rattus norvegicus
12.	ALA4105671	7b; 7b-m1	MRT	=	33.6	min	ALA4016673			hr	Rattus norvegicus
13.	ALA4105671	7b; 7b-m1	EC50	=	8.9	nM	ALA4016674	8.05		nM	Mus musculus
14.	ALA4105671	7b; 7b-m1	Emax	=	39	%	ALA4016656			%	Mus musculus
15.	ALA4105671	7b; 7b-m1	Activity		0		ALA4016675		Not Active		Mus musculus
16.	ALA4105671	7b; 7b-m1	Activity		0		ALA4016676		Active		Mus musculus
17.	ALA4105671	7b; 7b-m1	Activity		0		ALA4016677		Active		Mus musculus
18.	ALA4105671	7b; 7b-m1	Drug metabolism		0		ALA4016683		Metabolite_Detected		Homo sapiens
19.	ALA4105671	7b; 7b-m1	Activity		0		ALA4016662		Dose-dependent effect		Homo sapiens
20.	ALA4105671	7b; 7b-m1	Stability	=	101	%	ALA4016681			%	Homo sapiens