Activities

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Activities

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#	Name	Compound Key	Action Type	Relation	Activity Value	Units	Assay ID	Assay Description	Comment	Assay	Assay Organism
1.	ALA4108795	BDBM205423	Ki	=	0.5	nM	ALA3887929	9.30	363866	nM	Homo sapiens
2.	ALA4108795	BDBM205423	EC50	=	34	nM	ALA3887928	7.47	363857	nM	Homo sapiens
3.	ALA4108795	BDBM205423	BPR	>=	7.9		ALA4355774
4.	ALA4108795	BDBM205423	BPR	=	0.6		ALA4355773
5.	ALA4108795	BDBM205423	Drug uptake	=	0.025	nmol/g	ALA4355772			nmol/g
6.	ALA4108795	BDBM205423	Drug uptake	=	0.068	nmol/g	ALA4355771			nmol/g
7.	ALA4108795	BDBM205423	FC	=	1.65		ALA4355770				Rattus norvegicus
8.	ALA4108795	BDBM205423	FC	=	2.44		ALA4355769				Rattus norvegicus
9.	ALA4108795	BDBM205423	F	=	132	%	ALA4355768			%
10.	ALA4108795	BDBM205423	Vdss	=	1.79	L/Kg	ALA4355765			L.kg-1
11.	ALA4108795	BDBM205423	t1/2	=	1.71	hr	ALA4355762			hr
12.	ALA4108795	BDBM205423	CL	=	27.8	ml/min.kg	ALA4355760			mL.min-1.kg-1
13.	ALA4108795	BDBM205423	AUC/dose	=	3.36	uM.hr.kg/mg	ALA4355759			uM.hr.kg/mg
14.	ALA4108795	BDBM205423	Fu	=	88	%	ALA4355757
15.	ALA4108795	BDBM205423	EC50	=	34.4	nM	ALA4355755	7.46		nM	Rattus norvegicus
16.	ALA4108795	BDBM205423	Ki	=	0.55	nM	ALA4355754	9.26		nM	Homo sapiens
17.	ALA4108795	BDBM205423	Fu	=	96	%	ALA4355753
18.	ALA4108795	BDBM205423	Papp	=	5.3	10'-6 cm/s	ALA4355751			10'-6 cm/s
19.	ALA4108795	BDBM205423	Ki	=	790	nM	ALA4355756	6.10		nM	Homo sapiens