# | Name | Compound Key | Action Type | Relation | Activity Value | Units | Assay ID | Assay Description | Comment | Assay | Assay Organism | |
---|---|---|---|---|---|---|---|---|---|---|---|---|
1. | ALA4113501 | BDBM205425 | Ki | = | 1.4 | nM | ALA3887929 | 8.85 | 363868 | nM | Homo sapiens | |
2. | ALA4113501 | BDBM205425 | EC50 | = | 6 | nM | ALA3887928 | 8.22 | 363859 | nM | Homo sapiens | |
3. | ALA4113501 | BDBM205425 | FC | = | 34.18 | ALA4355744 | Rattus norvegicus | |||||
4. | ALA4113501 | BDBM205425 | AUC | = | 4.89 | nM.hr/g | ALA4355743 | nM.hr/g | ||||
5. | ALA4113501 | BDBM205425 | Tmax | = | 12 | hr | ALA4355746 | hr | ||||
6. | ALA4113501 | BDBM205425 | FC | = | 2.83 | ALA4355745 | Rattus norvegicus | |||||
7. | ALA4113501 | BDBM205425 | BPR | = | 3.03 | ALA4355774 | ||||||
8. | ALA4113501 | BDBM205425 | BPR | = | 1.56 | ALA4355773 | ||||||
9. | ALA4113501 | BDBM205425 | Drug uptake | = | 0.049 | nmol/g | ALA4355772 | nmol/g | ||||
10. | ALA4113501 | BDBM205425 | Drug uptake | = | 0.147 | nmol/g | ALA4355771 | nmol/g | ||||
11. | ALA4113501 | BDBM205425 | FC | = | 2.57 | ALA4355770 | Rattus norvegicus | |||||
12. | ALA4113501 | BDBM205425 | FC | = | 2.53 | ALA4355769 | Rattus norvegicus | |||||
13. | ALA4113501 | BDBM205425 | F | = | 49.7 | % | ALA4355768 | % | ||||
14. | ALA4113501 | BDBM205425 | Vdss | = | 10.3 | L/Kg | ALA4355765 | L.kg-1 | ||||
15. | ALA4113501 | BDBM205425 | t1/2 | = | 3.81 | hr | ALA4355762 | hr | ||||
16. | ALA4113501 | BDBM205425 | CL | = | 70.5 | ml/min.kg | ALA4355760 | mL.min-1.kg-1 | ||||
17. | ALA4113501 | BDBM205425 | AUC/dose | = | 0.43 | uM.hr.kg/mg | ALA4355759 | uM.hr.kg/mg | ||||
18. | ALA4113501 | BDBM205425 | Fu | = | 95 | % | ALA4355757 | |||||
19. | ALA4113501 | BDBM205425 | EC50 | = | 31.2 | nM | ALA4355755 | 7.51 | nM | Rattus norvegicus | ||
20. | ALA4113501 | BDBM205425 | Ki | = | 2.4 | nM | ALA4355754 | 8.62 | nM | Homo sapiens |