| # | Name | Compound Key | Action Type | Relation | Activity Value | Units | Assay ID | Assay Description | Comment | Assay | Assay Organism | |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1. |  ALA4128747 | 1.HCl | Drug uptake | = | 55 | nM | ALA4121726 | nM | Macaca fascicularis | |||
| 2. | ALA4128747 | 1.HCl | Drug uptake | = | 40 | nM | ALA4121725 | nM | Canis lupus familiaris | |||
| 3. | ALA4128747 | 1.HCl | Drug uptake | = | 51 | nM | ALA4121724 | nM | Rattus norvegicus | |||
| 4. | ALA4128747 | 1.HCl | F | = | 9 | % | ALA4121677 | % | Canis lupus familiaris | |||
| 5. | ALA4128747 | 1.HCl | F | = | 11.7 | % | ALA4121670 | % | Macaca fascicularis | |||
| 6. | ALA4128747 | 1.HCl | AUC/dose | = | 2 | microM.hr/mg/kg | ALA4121669 | microM.hr/mg/kg | Macaca fascicularis | |||
| 7. | ALA4128747 | 1.HCl | AUC | = | 4 | uM.hr | ALA4121668 | standard_value was converted from uM.hr to ng.hr.mL-1 using the parent compound MW | standard_value was converted from uM.hr to ug.hr.mL-1 using the parent compound MW | standard_value was converted from uM.hr to ug.hr.mL-1 using the parent compound MW | standard_value was converted from uM.hr to ug.hr.mL-1 using the parent compound MW | standard_value was converted from uM.hr to ug.hr.mL-1 using the parent compound MW | standard_value was converted from uM.hr to ug.hr.mL-1 using the parent compound MW | ng.hr.mL-1 | Macaca fascicularis | ||
| 8. | ALA4128747 | 1.HCl | Tmax | = | 4.7 | hr | ALA4121667 | hr | Macaca fascicularis | |||
| 9. | ALA4128747 | 1.HCl | Cmax | = | 0.18 | uM | ALA4121666 | nM | Macaca fascicularis | |||
| 10. | ALA4128747 | 1.HCl | t1/2eff | = | 17 | hr | ALA4121664 | hr | Macaca fascicularis | |||
| 11. | ALA4128747 | 1.HCl | beta t1/2 | = | 20 | hr | ALA4121665 | hr | Macaca fascicularis | |||
| 12. | ALA4128747 | 1.HCl | CL | = | 5.6 | ml/min.kg | ALA4121644 | mL.min-1.kg-1 | Rattus norvegicus | |||
| 13. | ALA4128747 | 1.HCl | Vdss | = | 3.7 | L/Kg | ALA4121645 | L.kg-1 | Rattus norvegicus | |||
| 14. | ALA4128747 | 1.HCl | t1/2eff | = | 7.6 | hr | ALA4121646 | hr | Rattus norvegicus | |||
| 15. | ALA4128747 | 1.HCl | beta t1/2 | = | 9.7 | hr | ALA4121647 | hr | Rattus norvegicus | |||
| 16. | ALA4128747 | 1.HCl | Cmax | = | 0.33 | uM | ALA4121648 | nM | Rattus norvegicus | |||
| 17. | ALA4128747 | 1.HCl | Tmax | = | 5.3 | hr | ALA4121649 | hr | Rattus norvegicus | |||
| 18. | ALA4128747 | 1.HCl | AUC | = | 5 | uM.hr | ALA4121650 | standard_value was converted from uM.hr to ng.hr.mL-1 using the parent compound MW | standard_value was converted from uM.hr to ug.hr.mL-1 using the parent compound MW | standard_value was converted from uM.hr to ug.hr.mL-1 using the parent compound MW | standard_value was converted from uM.hr to ug.hr.mL-1 using the parent compound MW | standard_value was converted from uM.hr to ug.hr.mL-1 using the parent compound MW | standard_value was converted from uM.hr to ug.hr.mL-1 using the parent compound MW | ng.hr.mL-1 | Rattus norvegicus | ||
| 19. | ALA4128747 | 1.HCl | AUC/dose | = | 1 | microM.hr/mg/kg | ALA4121651 | microM.hr/mg/kg | Rattus norvegicus | |||
| 20. | ALA4128747 | 1.HCl | F | = | 28 | % | ALA4121652 | % | Rattus norvegicus |
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