| # | Name | Compound Key | Action Type | Relation | Activity Value | Units | Assay ID | Assay Description | Comment | Assay | Assay Organism | |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1. |  ALA4128835 | 16 | IC50 | > | 50 | uM | ALA4122664 | nM | Homo sapiens | |||
| 2. | ALA4128835 | 16 | IC50 | > | 50 | uM | ALA4122663 | nM | Homo sapiens | |||
| 3. | ALA4128835 | 16 | IC50 | > | 50 | uM | ALA4122662 | nM | Homo sapiens | |||
| 4. | ALA4128835 | 16 | Activity | 0 | ALA4122628 | Not Active | Homo sapiens | |||||
| 5. | ALA4128835 | 16 | EC50 | = | 0.093 | uM | ALA4122629 | 7.03 | nM | Homo sapiens | ||
| 6. | ALA4128835 | 16 | IC50 | = | 30.8 | nM | ALA4122630 | 7.51 | nM | Rattus norvegicus | ||
| 7. | ALA4128835 | 16 | Vdss | = | 591 | ml/kg | ALA4122646 | L.kg-1 | Rattus norvegicus | |||
| 8. | ALA4128835 | 16 | CL | = | 100 | ml/hr/kg | ALA4122645 | mL.min-1.kg-1 | Rattus norvegicus | |||
| 9. | ALA4128835 | 16 | t1/2 | = | 7.32 | hr | ALA4122644 | hr | Rattus norvegicus | |||
| 10. | ALA4128835 | 16 | AUC | = | 3010 | ng.hr/ml | ALA4122643 | ng.hr.mL-1 | Rattus norvegicus | |||
| 11. | ALA4128835 | 16 | C0 | = | 1077 | ng/ml | ALA4122642 | ng/ml | Rattus norvegicus | |||
| 12. | ALA4128835 | 16 | F | = | 84.2 | % | ALA4122641 | % | Rattus norvegicus | |||
| 13. | ALA4128835 | 16 | t1/2 | = | 6.13 | hr | ALA4122640 | hr | Rattus norvegicus | |||
| 14. | ALA4128835 | 16 | AUC | = | 8445 | ng.hr/ml | ALA4122639 | ng.hr.mL-1 | Rattus norvegicus | |||
| 15. | ALA4128835 | 16 | Tmax | = | 0.81 | hr | ALA4122638 | hr | Rattus norvegicus | |||
| 16. | ALA4128835 | 16 | Cmax | = | 2188 | ng/ml | ALA4122637 | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | nM | Rattus norvegicus | ||
| 17. | ALA4128835 | 16 | CLH | = | 34 | microL/min/mg | ALA4122636 | mL.min-1.g-1 | ||||
| 18. | ALA4128835 | 16 | CLH | = | 68 | microL/min/mg | ALA4122635 | mL.min-1.g-1 | ||||
| 19. | ALA4128835 | 16 | IC50 | > | 50 | uM | ALA4122634 | nM | Homo sapiens | |||
| 20. | ALA4128835 | 16 | IC50 | > | 50 | uM | ALA4122661 | nM | Homo sapiens |
The page will load shortly, Thanks for your patience!