# | Name | Compound Key | Action Type | Relation | Activity Value | Units | Assay ID | Assay Description | Comment | Assay | Assay Organism | |
---|---|---|---|---|---|---|---|---|---|---|---|---|
1. | ALA4128926 | 1j | INH | = | -11 | % | ALA4121603 | % | Homo sapiens | |||
2. | ALA4128926 | 1j | INH | = | -4 | % | ALA4121602 | % | Homo sapiens | |||
3. | ALA4128926 | 1j | INH | = | -4 | % | ALA4121601 | % | Homo sapiens | |||
4. | ALA4128926 | 1j | INH | = | -10 | % | ALA4121600 | % | Homo sapiens | |||
5. | ALA4128926 | 1j | INH | = | -3 | % | ALA4121599 | % | Homo sapiens | |||
6. | ALA4128926 | 1j | INH | = | -2 | % | ALA4121598 | % | Homo sapiens | |||
7. | ALA4128926 | 1j | F | = | 20 | % | ALA4121593 | % | Rattus norvegicus | |||
8. | ALA4128926 | 1j | beta t1/2 | = | 2.1 | hr | ALA4121591 | hr | Rattus norvegicus | |||
9. | ALA4128926 | 1j | AUC | = | 328 | hr.ng/ml | ALA4121589 | ng.hr.mL-1 | Rattus norvegicus | |||
10. | ALA4128926 | 1j | Tmax | = | 0.8 | hr | ALA4121587 | hr | Rattus norvegicus | |||
11. | ALA4128926 | 1j | Cmax | = | 130 | ng/ml | ALA4121585 | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | nM | Rattus norvegicus | ||
12. | ALA4128926 | 1j | t1/2 | = | 0.7 | hr | ALA4121583 | hr | Rattus norvegicus | |||
13. | ALA4128926 | 1j | C0 | = | 4429 | ng/ml | ALA4121581 | ng/ml | Rattus norvegicus | |||
14. | ALA4128926 | 1j | AUC | = | 325 | hr.ng/ml | ALA4121579 | ng.hr.mL-1 | Rattus norvegicus | |||
15. | ALA4128926 | 1j | Vdss | = | 1.1 | L/Kg | ALA4121577 | L.kg-1 | Rattus norvegicus | |||
16. | ALA4128926 | 1j | CL | = | 51.4 | ml/min.kg | ALA4121575 | mL.min-1.kg-1 | Rattus norvegicus | |||
17. | ALA4128926 | 1j | INH | > | 10 | uM | ALA4121573 | uM | Homo sapiens | |||
18. | ALA4128926 | 1j | INH | > | 10 | uM | ALA4121572 | uM | Homo sapiens | |||
19. | ALA4128926 | 1j | INH | = | 9.9 | uM | ALA4121571 | uM | Homo sapiens | |||
20. | ALA4128926 | 1j | INH | = | 3.8 | uM | ALA4121570 | uM | Homo sapiens |