# | Name | Compound Key | Action Type | Relation | Activity Value | Units | Assay ID | Assay Description | Comment | Assay | Assay Organism | |
---|---|---|---|---|---|---|---|---|---|---|---|---|
1. | ALA4129161 | 1 | INH | 0 | ALA4323748 | Active | % | |||||
2. | ALA4129161 | 1 | Kd | = | 3 | nM | ALA5057939 | 8.52 | nM | |||
3. | ALA4129161 | 1 | IC50 | = | 1.28 | uM | ALA5057938 | 5.89 | nM | |||
4. | ALA4129161 | 1 | MIC100 | = | 0.78 | ug ml-1 | ALA4125298 | ug ml-1 | Aspergillus fumigatus | |||
5. | ALA4129161 | 1 | MIC100 | = | 0.08 | ug ml-1 | ALA4125297 | ug ml-1 | Aspergillus fumigatus | |||
6. | ALA4129161 | 1 | MIC100 | = | 0.29 | ug ml-1 | ALA4125296 | ug ml-1 | Aspergillus fumigatus | |||
7. | ALA4129161 | 1 | t1/2 | = | 98 | min | ALA4125295 | hr | ||||
8. | ALA4129161 | 1 | CLH | = | 34 | ml/min.kg | ALA4125294 | mL.min-1.kg-1 | ||||
9. | ALA4129161 | 1 | CLH | = | 55 | ml/min.kg | ALA4125293 | mL.min-1.kg-1 | ||||
10. | ALA4129161 | 1 | t1/2 | = | 91 | min | ALA4125292 | hr | ||||
11. | ALA4129161 | 1 | CLH | = | 21 | ml/min.kg | ALA4125291 | mL.min-1.kg-1 | ||||
12. | ALA4129161 | 1 | CLH | = | 31 | ml/min.kg | ALA4125290 | mL.min-1.kg-1 | ||||
13. | ALA4129161 | 1 | t1/2 | = | 166 | min | ALA4125289 | hr | ||||
14. | ALA4129161 | 1 | CLH | = | 5.54 | ml/min.kg | ALA4125288 | mL.min-1.kg-1 | ||||
15. | ALA4129161 | 1 | CLH | = | 7.53 | ml/min.kg | ALA4125287 | mL.min-1.kg-1 | ||||
16. | ALA4129161 | 1 | Ratio | = | 4 | ALA4125286 | ||||||
17. | ALA4129161 | 1 | Ratio | = | 22 | ALA4125285 | Candida albicans (strain SC5314 / ATCC MYA-2876) (Yeast) | |||||
18. | ALA4129161 | 1 | Kd(app) | = | 57 | nM | ALA4125284 | 7.24 | nM | Aspergillus | ||
19. | ALA4129161 | 1 | Kd(app) | = | 13 | nM | ALA4125283 | 7.89 | nM | Candida albicans (strain SC5314 / ATCC MYA-2876) (Yeast) | ||
20. | ALA4129161 | 1 | logP | = | 4.88 | ALA4125282 |