# | Name | Compound Key | Action Type | Relation | Activity Value | Units | Assay ID | Assay Description | Comment | Assay | Assay Organism | |
---|---|---|---|---|---|---|---|---|---|---|---|---|
1. | ALA4159416 | 14 | EC50 | > | 10 | uM | ALA4151317 | nM | Homo sapiens | |||
2. | ALA4159416 | 14 | logD | = | 2.94 | ALA4151316 | ||||||
3. | ALA4159416 | 14 | Drug metabolism | = | 67 | % | ALA4151300 | % | ||||
4. | ALA4159416 | 14 | Drug metabolism | = | 67 | % | ALA4151299 | % | ||||
5. | ALA4159416 | 14 | IC50 | = | 1.4 | uM | ALA4151281 | 5.85 | nM | Homo sapiens | ||
6. | ALA4159416 | 14 | F | = | 50 | % | ALA4151271 | % | Rattus norvegicus | |||
7. | ALA4159416 | 14 | t1/2eff | = | 3.5 | hr | ALA4151270 | hr | Rattus norvegicus | |||
8. | ALA4159416 | 14 | Vdss | = | 0.41 | L/Kg | ALA4151269 | L.kg-1 | Rattus norvegicus | |||
9. | ALA4159416 | 14 | CL | = | 3.1 | ml/min.kg | ALA4151268 | mL.min-1.kg-1 | Rattus norvegicus | |||
10. | ALA4159416 | 14 | Fu | = | 0.005 | ALA4151267 | ||||||
11. | ALA4159416 | 14 | Cp | = | 3 | uM | ALA4151266 | uM | Rattus norvegicus | |||
12. | ALA4159416 | 14 | MED | = | 10 | mg kg-1 | ALA4151265 | mg kg-1 | Rattus norvegicus | |||
13. | ALA4159416 | 14 | max activation | > | 370 | % | ALA4151264 | % | Rattus norvegicus | |||
14. | ALA4159416 | 14 | EC50 | = | 1.2 | nM | ALA4151263 | 8.92 | nM | Rattus norvegicus | ||
15. | ALA4159416 | 14 | EC50 | = | 127 | nM | ALA4151259 | 6.90 | nM | Homo sapiens | ||
16. | ALA4159416 | 14 | INH | = | 103 | % | ALA4151260 | % | Rattus norvegicus | |||
17. | ALA4159416 | 14 | INH | = | 102 | % | ALA4151260 | % | Rattus norvegicus | |||
18. | ALA4159416 | 14 | max activation | > | 179 | % | ALA4151261 | % | Homo sapiens | |||
19. | ALA4159416 | 14 | max activation | > | 179 | % | ALA4151261 | % | Homo sapiens | |||
20. | ALA4159416 | 14 | EC50 | = | 1.1 | nM | ALA4151258 | 8.96 | nM | Homo sapiens |