| # | Name | Compound Key | Action Type | Relation | Activity Value | Units | Assay ID | Assay Description | Comment | Assay | Assay Organism | |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1. |  ALA4159767 | 14; MK-8282 | %max | = | 99 | % | ALA4149815 | % | Mus musculus | |||
| 2. | ALA4159767 | 14; MK-8282 | %max | = | 92 | % | ALA4149814 | % | Homo sapiens | |||
| 3. | ALA4159767 | 14; MK-8282 | Fu | = | 1 | % | ALA4149850 | |||||
| 4. | ALA4159767 | 14; MK-8282 | Activity | 0 | ALA4149849 | Active | Rattus norvegicus | |||||
| 5. | ALA4159767 | 14; MK-8282 | Activity | 0 | ALA4149848 | Active | Rattus norvegicus | |||||
| 6. | ALA4159767 | 14; MK-8282 | Activity | 0 | ALA4149846 | Active | Mus musculus | |||||
| 7. | ALA4159767 | 14; MK-8282 | Activity | 0 | ALA4149845 | Active | Mus musculus | |||||
| 8. | ALA4159767 | 14; MK-8282 | Activity | 0 | ALA4149843 | Not Active | Mus musculus | |||||
| 9. | ALA4159767 | 14; MK-8282 | Activity | 0 | ALA4149842 | Active | Mus musculus | |||||
| 10. | ALA4159767 | 14; MK-8282 | Activity | 0 | ALA4149841 | Active | Mus musculus | |||||
| 11. | ALA4159767 | 14; MK-8282 | Cmax | = | 60 | nM | ALA4149840 | nM | Mus musculus | |||
| 12. | ALA4159767 | 14; MK-8282 | Activity | = | 50 | % | ALA4149839 | % | Mus musculus | |||
| 13. | ALA4159767 | 14; MK-8282 | Activity | = | 49 | % | ALA4149838 | % | Mus musculus | |||
| 14. | ALA4159767 | 14; MK-8282 | Activity | = | 46 | % | ALA4149837 | % | Mus musculus | |||
| 15. | ALA4159767 | 14; MK-8282 | Activity | = | 23 | % | ALA4149836 | % | Mus musculus | |||
| 16. | ALA4159767 | 14; MK-8282 | Activity | = | 21 | % | ALA4149835 | % | Mus musculus | |||
| 17. | ALA4159767 | 14; MK-8282 | Activity | 0 | ALA4149834 | Dose-dependent effect | Mus musculus | |||||
| 18. | ALA4159767 | 14; MK-8282 | AUC | = | 131 | uM.hr | ALA4149833 | standard_value was converted from uM.hr to ng.hr.mL-1 using the parent compound MW | standard_value was converted from uM.hr to ug.hr.mL-1 using the parent compound MW | standard_value was converted from uM.hr to ug.hr.mL-1 using the parent compound MW | standard_value was converted from uM.hr to ug.hr.mL-1 using the parent compound MW | standard_value was converted from uM.hr to ug.hr.mL-1 using the parent compound MW | standard_value was converted from uM.hr to ug.hr.mL-1 using the parent compound MW | ng.hr.mL-1 | Canis lupus familiaris | ||
| 19. | ALA4159767 | 14; MK-8282 | t1/2 | = | 70 | hr | ALA4149832 | hr | Canis lupus familiaris | |||
| 20. | ALA4159767 | 14; MK-8282 | Vdss | = | 4.4 | L/Kg | ALA4149831 | L.kg-1 | Canis lupus familiaris |
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