| # | Name | Compound Key | Action Type | Relation | Activity Value | Units | Assay ID | Assay Description | Comment | Assay | Assay Organism | |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1. |  ALA4161327 | 8 | INH | 0 | ALA4135630 | Active | % | Rattus norvegicus | ||||
| 2. | ALA4161327 | 8 | INH | 0 | ALA4135629 | Active | % | Rattus norvegicus | ||||
| 3. | ALA4161327 | 8 | INH | 0 | ALA4135628 | Active | % | Rattus norvegicus | ||||
| 4. | ALA4161327 | 8 | INH | 0 | ALA4135627 | Active | % | Rattus norvegicus | ||||
| 5. | ALA4161327 | 8 | INH | 0 | ALA4135626 | Active | % | Rattus norvegicus | ||||
| 6. | ALA4161327 | 8 | INH | 0 | ALA4135625 | Active | % | Rattus norvegicus | ||||
| 7. | ALA4161327 | 8 | INH | 0 | ALA4135623 | Active | % | Rattus norvegicus | ||||
| 8. | ALA4161327 | 8 | INH | 0 | ALA4135624 | Active | % | Homo sapiens | ||||
| 9. | ALA4161327 | 8 | IC50 | = | 0.03 | uM | ALA4135616 | 7.52 | nM | Homo sapiens | ||
| 10. | ALA4161327 | 8 | IC50 | = | 0.067 | uM | ALA4135615 | 7.17 | nM | Rattus norvegicus | ||
| 11. | ALA4161327 | 8 | IC50 | = | 0.012 | uM | ALA4135614 | 7.92 | nM | Mus musculus | ||
| 12. | ALA4161327 | 8 | INH | 0 | ALA4135614 | Dose-dependent effect | % | Mus musculus | ||||
| 13. | ALA4161327 | 8 | F | = | 135.3 | % | ALA4135613 | % | Canis lupus familiaris | |||
| 14. | ALA4161327 | 8 | Cmax | = | 2343 | nM | ALA4135612 | nM | Canis lupus familiaris | |||
| 15. | ALA4161327 | 8 | AUC | = | 15391 | nM.hr | ALA4135611 | standard_value was converted from uM.hr to ng.hr.mL-1 using the parent compound MW | standard_value was converted from uM.hr to ug.hr.mL-1 using the parent compound MW | standard_value was converted from uM.hr to ug.hr.mL-1 using the parent compound MW | standard_value was converted from uM.hr to ug.hr.mL-1 using the parent compound MW | standard_value was converted from uM.hr to ug.hr.mL-1 using the parent compound MW | standard_value was converted from uM.hr to ug.hr.mL-1 using the parent compound MW | ng.hr.mL-1 | Canis lupus familiaris | ||
| 16. | ALA4161327 | 8 | AUC | = | 2844 | nM.hr | ALA4135610 | standard_value was converted from uM.hr to ng.hr.mL-1 using the parent compound MW | standard_value was converted from uM.hr to ug.hr.mL-1 using the parent compound MW | standard_value was converted from uM.hr to ug.hr.mL-1 using the parent compound MW | standard_value was converted from uM.hr to ug.hr.mL-1 using the parent compound MW | standard_value was converted from uM.hr to ug.hr.mL-1 using the parent compound MW | standard_value was converted from uM.hr to ug.hr.mL-1 using the parent compound MW | ng.hr.mL-1 | Canis lupus familiaris | ||
| 17. | ALA4161327 | 8 | t1/2 | = | 5 | hr | ALA4135609 | hr | Canis lupus familiaris | |||
| 18. | ALA4161327 | 8 | Vdss | = | 2 | L/Kg | ALA4135608 | L.kg-1 | Canis lupus familiaris | |||
| 19. | ALA4161327 | 8 | CL | = | 7.8 | ml/min.kg | ALA4135607 | mL.min-1.kg-1 | Canis lupus familiaris | |||
| 20. | ALA4161327 | 8 | F | = | 130.1 | % | ALA4135606 | % | Rattus norvegicus |
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