# | Name | Compound Key | Action Type | Relation | Activity Value | Units | Assay ID | Assay Description | Comment | Assay | Assay Organism | |
---|---|---|---|---|---|---|---|---|---|---|---|---|
1. | ALA4161754 | 28; ORIC-101 | INH | 0 | ALA4151849 | Dose-dependent effect | % | Homo sapiens | ||||
2. | ALA4161754 | 28; ORIC-101 | INH | 0 | ALA4151846 | Dose-dependent effect | % | Sus scrofa | ||||
3. | ALA4161754 | 28; ORIC-101 | Activity | 0 | ALA4151855 | Active | Homo sapiens | |||||
4. | ALA4161754 | 28; ORIC-101 | Activity | 0 | ALA4151854 | Active | Homo sapiens | |||||
5. | ALA4161754 | 28; ORIC-101 | TGI | 0 | ALA4151852 | Not Active | Homo sapiens | |||||
6. | ALA4161754 | 28; ORIC-101 | Cp(f) | = | 0.02 | uM | ALA4151851 | uM | ||||
7. | ALA4161754 | 28; ORIC-101 | INH | 0 | ALA4151850 | Dose-dependent effect | % | Mus musculus | ||||
8. | ALA4161754 | 28; ORIC-101 | IC50 | = | 21.2 | nM | ALA4151849 | 7.67 | nM | Homo sapiens | ||
9. | ALA4161754 | 28; ORIC-101 | IC50 | = | 17.2 | nM | ALA4151848 | 7.76 | nM | Homo sapiens | ||
10. | ALA4161754 | 28; ORIC-101 | IC50 | = | 39.3 | nM | ALA4151847 | 7.41 | nM | Sus scrofa | ||
11. | ALA4161754 | 28; ORIC-101 | IC50 | = | 181 | nM | ALA4151846 | 6.74 | nM | Sus scrofa | ||
12. | ALA4161754 | 28; ORIC-101 | IC50 | = | 11.1 | nM | ALA4151845 | 7.96 | nM | |||
13. | ALA4161754 | 28; ORIC-101 | IC50 | = | 14.9 | nM | ALA4151844 | 7.83 | nM | |||
14. | ALA4161754 | 28; ORIC-101 | IC50 | = | 24.5 | nM | ALA4151843 | 7.61 | nM | Canis lupus familiaris | ||
15. | ALA4161754 | 28; ORIC-101 | IC50 | = | 34.3 | nM | ALA4151842 | 7.46 | nM | Canis lupus familiaris | ||
16. | ALA4161754 | 28; ORIC-101 | IC50 | = | 45.6 | nM | ALA4151841 | 7.34 | nM | Rattus norvegicus | ||
17. | ALA4161754 | 28; ORIC-101 | IC50 | = | 59.4 | nM | ALA4151840 | 7.23 | nM | Rattus norvegicus | ||
18. | ALA4161754 | 28; ORIC-101 | IC50 | = | 19.5 | nM | ALA4151839 | 7.71 | nM | Homo sapiens | ||
19. | ALA4161754 | 28; ORIC-101 | IC50 | = | 24.9 | nM | ALA4151838 | 7.60 | nM | Homo sapiens | ||
20. | ALA4161754 | 28; ORIC-101 | INH | 0 | ALA4151837 | Not Active | % | Homo sapiens |