# | Name | Compound Key | Action Type | Relation | Activity Value | Units | Assay ID | Assay Description | Comment | Assay | Assay Organism | |
---|---|---|---|---|---|---|---|---|---|---|---|---|
1. | ALA4161935 | 15b | IC50 | = | 89.28 | nM | ALA4150706 | 7.05 | nM | Influenza B virus (strain B/Lee/1940) | ||
2. | ALA4161935 | 15b | Drug metabolism | 0 | ALA4150705 | Metabolite_Detected | ||||||
3. | ALA4161935 | 15b | Activity | 0 | ALA4150704 | Non-Toxic | Mus musculus | |||||
4. | ALA4161935 | 15b | Activity | 0 | ALA4150703 | Non-Toxic | Mus musculus | |||||
5. | ALA4161935 | 15b | Stability | = | 120.7 | % | ALA4150702 | % | ||||
6. | ALA4161935 | 15b | Stability | = | 119.9 | % | ALA4150701 | % | ||||
7. | ALA4161935 | 15b | Stability | = | 119.5 | % | ALA4150700 | % | ||||
8. | ALA4161935 | 15b | Stability | = | 117.5 | % | ALA4150699 | % | ||||
9. | ALA4161935 | 15b | Stability | = | 100 | % | ALA4150698 | % | ||||
10. | ALA4161935 | 15b | Stability | = | 95.4 | % | ALA4150697 | % | ||||
11. | ALA4161935 | 15b | Stability | = | 82.7 | % | ALA4150696 | % | ||||
12. | ALA4161935 | 15b | CLH | < | 8.6 | ml/min.kg | ALA4150695 | mL.min-1.kg-1 | ||||
13. | ALA4161935 | 15b | CLH | < | 9.6 | uL/min | ALA4150694 | uL/min | ||||
14. | ALA4161935 | 15b | t1/2 | > | 145 | min | ALA4150693 | hr | ||||
15. | ALA4161935 | 15b | CC50 | > | 250 | uM | ALA4150692 | nM | Canis lupus familiaris | |||
16. | ALA4161935 | 15b | EC50 | = | 1.7 | uM | ALA4150691 | 5.77 | nM | Influenza A virus | ||
17. | ALA4161935 | 15b | EC50 | = | 0.07 | uM | ALA4150690 | 7.16 | nM | Influenza A virus | ||
18. | ALA4161935 | 15b | Ratio EC50 | = | 6 | ALA4150688 | Influenza A virus | |||||
19. | ALA4161935 | 15b | Ratio IC50 | = | 4 | ALA4150687 | Influenza A virus | |||||
20. | ALA4161935 | 15b | EC50 | = | 0.61 | uM | ALA4150684 | 6.21 | nM | Influenza A virus |