# | Name | Compound Key | Action Type | Relation | Activity Value | Units | Assay ID | Assay Description | Comment | Assay | Assay Organism | |
---|---|---|---|---|---|---|---|---|---|---|---|---|
1. | ALA4162598 | 5 | solubility | > | 460 | ug ml-1 | ALA4158599 | ug.mL-1 | ||||
2. | ALA4162598 | 5 | Drug metabolism | 0 | ALA4158625 | Metabolite_Detected | ||||||
3. | ALA4162598 | 5 | Drug metabolism | 0 | ALA4158624 | Metabolite_Detected | ||||||
4. | ALA4162598 | 5 | Drug metabolism | 0 | ALA4158623 | Metabolite_Detected | ||||||
5. | ALA4162598 | 5 | Drug metabolism | 0 | ALA4158622 | Metabolite_Detected | ||||||
6. | ALA4162598 | 5 | IC50 | = | 2.3 | uM | ALA4158617 | 5.64 | nM | Human respiratory syncytial virus | ||
7. | ALA4162598 | 5 | t1/2 | = | 12 | hr | ALA4158602 | hr | Rattus norvegicus | |||
8. | ALA4162598 | 5 | CLH | = | 19 | ml/min.kg | ALA4158594 | mL.min-1.kg-1 | ||||
9. | ALA4162598 | 5 | CLH | = | 10 | ml/min.kg | ALA4158593 | mL.min-1.kg-1 | ||||
10. | ALA4162598 | 5 | F | = | 32 | % | ALA4158592 | % | Rattus norvegicus | |||
11. | ALA4162598 | 5 | Vdss | = | 73 | L/Kg | ALA4158591 | L.kg-1 | Rattus norvegicus | |||
12. | ALA4162598 | 5 | CL | = | 89 | ml/min.kg | ALA4158590 | mL.min-1.kg-1 | Rattus norvegicus | |||
13. | ALA4162598 | 5 | AUC | = | 510 | hr.ng/ml | ALA4158589 | ng.hr.mL-1 | Rattus norvegicus | |||
14. | ALA4162598 | 5 | AUC | = | 324 | hr.ng/ml | ALA4158588 | ng.hr.mL-1 | Rattus norvegicus | |||
15. | ALA4162598 | 5 | CLH | = | 23 | ml/min.kg | ALA4158587 | mL.min-1.kg-1 | ||||
16. | ALA4162598 | 5 | Peff | = | 0.99 | ucm/s | ALA4158586 | ucm/s | ||||
17. | ALA4162598 | 5 | Ratio CC50/EC50 | = | 115 | ALA4158585 | ||||||
18. | ALA4162598 | 5 | CC50 | = | 23 | uM | ALA4158584 | nM | Homo sapiens | |||
19. | ALA4162598 | 5 | EC50 | = | 0.2 | uM | ALA4158583 | 6.70 | nM | Human respiratory syncytial virus |