# | Name | Compound Key | Action Type | Relation | Activity Value | Units | Assay ID | Assay Description | Comment | Assay | Assay Organism | |
---|---|---|---|---|---|---|---|---|---|---|---|---|
1. | ALA4162778 | 16 | EC50 | > | 10 | uM | ALA4151317 | nM | Homo sapiens | |||
2. | ALA4162778 | 16 | logD | = | 2.25 | ALA4151316 | ||||||
3. | ALA4162778 | 16 | IC50 | = | 0.3 | uM | ALA4151281 | 6.52 | nM | Homo sapiens | ||
4. | ALA4162778 | 16 | F | = | 50 | % | ALA4151271 | % | Rattus norvegicus | |||
5. | ALA4162778 | 16 | t1/2eff | = | 6.2 | hr | ALA4151270 | hr | Rattus norvegicus | |||
6. | ALA4162778 | 16 | Vdss | = | 0.35 | L/Kg | ALA4151269 | L.kg-1 | Rattus norvegicus | |||
7. | ALA4162778 | 16 | CL | = | 1.1 | ml/min.kg | ALA4151268 | mL.min-1.kg-1 | Rattus norvegicus | |||
8. | ALA4162778 | 16 | Fu | = | 0.003 | ALA4151267 | ||||||
9. | ALA4162778 | 16 | Cp | = | 13.9 | uM | ALA4151266 | uM | Rattus norvegicus | |||
10. | ALA4162778 | 16 | MED | = | 30 | mg kg-1 | ALA4151265 | mg kg-1 | Rattus norvegicus | |||
11. | ALA4162778 | 16 | max activation | > | 370 | % | ALA4151264 | % | Rattus norvegicus | |||
12. | ALA4162778 | 16 | EC50 | = | 2.3 | nM | ALA4151263 | 8.64 | nM | Rattus norvegicus | ||
13. | ALA4162778 | 16 | EC50 | = | 1379 | nM | ALA4151259 | 5.86 | nM | Homo sapiens | ||
14. | ALA4162778 | 16 | EC50 | = | 247 | nM | ALA4151259 | 6.61 | nM | Homo sapiens | ||
15. | ALA4162778 | 16 | INH | = | 99 | % | ALA4151260 | % | Rattus norvegicus | |||
16. | ALA4162778 | 16 | INH | = | 100 | % | ALA4151260 | % | Rattus norvegicus | |||
17. | ALA4162778 | 16 | EC50 | = | 1.7 | nM | ALA4151258 | 8.77 | nM | Homo sapiens | ||
18. | ALA4162778 | 16 | EC50 | = | 3.1 | nM | ALA4151258 | 8.51 | nM | Homo sapiens | ||
19. | ALA4162778 | 16 | max activation | > | 179 | % | ALA4151262 | % | Homo sapiens | |||
20. | ALA4162778 | 16 | max activation | > | 179 | % | ALA4151262 | % | Homo sapiens |